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hydramethylnon (CID 5281875) - Compound BioActivity Data
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BioActivity Outcomes:
Active(46)
 
 
Inactive(29)
 
 
Inconclusive(57)
 
 
Unspecified(10)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD Fxr(6)
 
 
 
BioAssay Types:
Confirmatory(93)
 
 
 
 
Summary(24)
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(111)
 
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 134    Data Row: 142   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213478]
Potency-Replicate_1 1.2197qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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2
[SID144213478]
AhR Potency (uM) 1.93312qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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3
[SID144213478]
Potency-Replicate_1 3.0638qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID144213478]
Potency-Replicate_1 3.8571qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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5
[SID144213478]
Potency-Replicate_1 4.3277qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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6
[SID144213478]
Potency-Replicate_1 4.3277qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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7
[SID144213478]
Potency-Replicate_1 6.9167qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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8
[SID144213478]
Potency-Replicate_1 6.9167qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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9
[SID144213478]
Ratio Potency (uM) 7.46844qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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10
[SID144213478]
Potency-Replicate_1 7.7606qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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11
[SID144213478]
Potency-Replicate_1 8.6349qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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12
[SID144213478]
Potency-Replicate_1 8.6349qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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13
[SID144213478]
Potency-Replicate_1 9.77qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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14
[SID144213478]
Potency-Replicate_1 10.9622qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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15
[SID144213478]
Potency-Replicate_1 10.9622qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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16
[SID144213478]
Potency-Replicate_1 12.1972qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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17
[SID144213478]
Potency-Replicate_1 12.1972qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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18
[SID144213478]
Potency-Replicate_1 13.6854qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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19
[SID144213478]
Potency-Replicate_1 13.8006qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway [AID743223, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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20
[SID26757187]
Potency 14.1254qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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