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Ellagic Acid (CID 5281855) - Compound BioActivity Data
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BioActivity Outcomes:
Active(276)
 
 
Inactive(816)
 
 
Inconclusive(126)
 
 
Unspecified(145)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(20)
 
 
NR LBD PPAR(15)
 
 
Bcl-2 like(15)
 
 
 
PLDc mTdp1 2(12)
 
 
 
 
BioAssay Types:
Confirmatory(550)
 
 
 
 
 
Screening(395)
 
 
 
 
 
Literature(317)
 
 
 
 
 
Summary(25)
 
 
 
 
BioActivity Types:
Potency(410)
 
 
 
 
 
IC50(138)
 
 
 
 
 
Ki(22)
 
 
 
EC50(11)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1086    Data Row: 1363   Total Pages: 69   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26748644]
Potency 0.004Confirmation Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID489007, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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2
[SID103163815]
GI50 0.01Growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program [AID247402, Type: Literature]
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3
[SID26748644]
Potency 0.0112qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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4
[SID26748644]
Potency 0.0141Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2572, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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5
[SID103163815]
Ki 0.02Inhibition of rat liver CK2 by Lineweaver-Burke double reciprocal plot analysis [AID352791, Type: Literature]
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6
[SID170481926]
Ki 0.02Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Human Ck2 Alpha Complexed With Ellagic Acid [gi:225697983]
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7
[SID170481926]
Ki 0.02Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Human Ck2 Alpha Complexed With Ellagic Acid [gi:225697983]
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8
[SID103163815]
IC50 0.04Inhibition of rat liver CK2 catalytic activity [AID352792, Type: Literature]
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9
[SID103163815]
IC50 0.04Inhibition of rat liver CK2 [AID262917, Type: Literature]
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10
[SID103163815]
IC50 0.04Inhibition of CK2 in rat liver [AID317243, Type: Literature]
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11
[SID103163815]
IC50 0.04Inhibition of human recombinant CK2 expressed in Escherichia coli BL21(DE3) using RRRDDDSDDD as substrate after 15 mins by capillary electrophoretic analysis [AID757709, Type: Literature]
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12
[SID103163815]
IC50 0.04Inhibition of GST-fused human recombinant CK2alpha expressed in Escherichia coli HMS174 (DE3) [AID352795, Type: Literature]Casein kinase II subunit alpha [gi:55977123]
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13
[SID87544482]
IC50 0.04187Late stage results for the probe development effort to identify inhibitors of tRNA 2'-phosphotransferase (TPT1): Fluorescence polarization-based biochemical dose response assay for TPT1 inhibitors [AID2838, Type: confirmatory]likely tRNA 2'-phosphotransferase [Candida albicans SC5314] [gi:68476498]
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14
[SID8139882]
Potency 0.0447qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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15
[SID26748644]
Potency 0.0708qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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16
[SID103163815]
Ki 0.081Reaction rate parameter value for phosphate with transfer with respect to ATP [AID17435, Type: Literature]
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17
[SID26748644]
Potency 0.0891Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Assay [AID2564, Type: confirmatory]
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18
[SID103163815]
IC50 0.1Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 mins [AID663960, Type: confirmatory]G-protein coupled receptor 35 [gi:68068087]
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19
[SID26748644]
Potency 0.1qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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20
[SID26753737]
Potency 0.1qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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