daidzein (CID 5281708) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(69)
 
 
Inactive(894)
 
 
Inconclusive(122)
 
 
Unspecified(112)
 
 
Top Targets:
NR LBD TR(20)
 
 
 
p450(16)
 
 
 
 
 
PLN02808(15)
 
 
7TM GPCR Srx(15)
 
 
 
HELICc(15)
 
 
 
BioAssay Types:
Confirmatory(633)
 
 
 
 
 
Screening(327)
 
 
 
 
Literature(143)
 
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(529)
 
 
 
 
 
IC50(59)
 
 
 
 
 
Ki(3)
 
 
 
EC50(1)
 
 
Kd(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 872    Data Row: 1197   Total Pages: 24   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103166710]
Ki 0.3Inhibition of binding of 17 beta-estradiol to human Estrogen receptor beta [AID70660, Type: Literature]
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2
[SID103166710]
IC50 0.303Binding affinity against human estrogen receptor beta (ER beta) in competitive binding assay [AID70514, Type: Literature]
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3
[SID103166710]
IC50 0.45Displacement of fluorescent labeled ES2 from recombinant ERalpha [AID499822, Type: Literature]
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4
[SID17389519]
Potency 0.7943qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID17389519]
Potency 0.7943qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID17389519]
Potency 0.7943qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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7
[SID17389519]
Potency 0.7943qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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8
[SID50126369]
Potency 0.8913qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID50126369]
Potency 0.8913qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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10
[SID50126369]
Potency 0.8913qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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11
[SID50126369]
Potency 0.8913qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID103166710]
IC50 1.1Inhibition of binding of 17 beta-estradiol to human Estrogen receptor beta [AID70654, Type: Literature]
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13
[SID103166710]
IC50 1.2Estrogenic activity in human Ishikawa cells assessed as induction of alkaline phosphatase activity after 4 days by para-nitrophenol release assay [AID361464, Type: Literature]
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14
[SID103166710]
IC50 1.2Displacement of [3H]estradiol from human recombinant ERbeta [AID361463, Type: Literature]Estrogen receptor beta [gi:6166154]
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15
[SID103166710]
IC50 1.2Displacement of [3H]estradiol from human recombinant ERbeta [AID361463, Type: Literature]Estrogen receptor beta [gi:6166154]
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16
[SID103166710]
IC50 1.2Displacement of [3H]estradiol from human recombinant ERbeta [AID361463, Type: Literature]Estrogen receptor beta [gi:6166154]
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17
[SID103166710]
Ki 1.8Inhibition of binding of 17 beta-estradiol to human Estrogen receptor alpha [AID70353, Type: Literature]
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18
[SID103166710]
IC50 2.16Binding affinity against human estrogen receptor alpha in competitive binding assay [AID70199, Type: Literature]
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19
[SID103166710]
IC50 2.8Binding affinity for human Estrogen receptor beta [AID240680, Type: Literature]Estrogen receptor beta [gi:6166154]
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20
[SID103166710]
IC50 2.8Binding affinity for human Estrogen receptor beta [AID240680, Type: Literature]Estrogen receptor beta [gi:6166154]
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21
[SID103166710]
IC50 2.8Binding affinity for human Estrogen receptor beta [AID240680, Type: Literature]Estrogen receptor beta [gi:6166154]
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22
[SID103166710]
Kd 5.9Displacement of [3H]-estradiol (E2) frrom sheep uterine estrogen receptor [AID69702, Type: Literature]
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23
[SID103166710]
IC50 6.3Inhibition of binding of 17 beta-estradiol to human Estrogen receptor alpha [AID70335, Type: Literature]
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24
[SID11114077]
Potency 6.3096qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
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25
[SID11114077]
Potency 6.3096qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
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26
[SID11114077]
Potency 6.3096qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
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27
[SID90341229]
Potency 8.4368qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1) [AID488773, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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28
[SID90341229]
Potency 8.4368qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1) [AID488773, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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29
[SID103166710]
IC50 9Inhibition of Hamster Liver mitochondrial ALDH-2 [AID31427, Type: Literature]
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30
[SID103166710]
IC50 9Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 [AID34047, Type: Literature]
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31
[SID103166710]
IC50 9Inhibition of hamster liver ALDH2 [AID341733, Type: Literature]
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32
[SID90341229]
Potency 9.2qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]NPC1 gene product [Homo sapiens] [gi:255652944]
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33
[SID11114077]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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34
[SID11114077]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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35
[SID11114077]
Potency 10qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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36
[SID11114077]
Potency 10qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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37
[SID11114077]
Potency 10qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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38
[SID11114077]
Potency 10qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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39
[SID11114077]
Potency 10qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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40
[SID90341229]
Potency 10qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]RAB9A gene product [Homo sapiens] [gi:4759012]
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41
[SID50104845]
Potency 12.5893qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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42
[SID50104845]
Potency 12.5893qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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43
[SID103166710]
IC50 13.63Inhibition of ALR2 (aldose reductase) of bovine lens [AID34338, Type: Literature]Aldose reductase [gi:113594]
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44
[SID103166710]
IC50 14Inhibition of Hamster Liver mitochondrial Monoamine oxidase. [AID125222, Type: Literature]
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45
[SID103166710]
IC50 14Inhibition of hamster liver mitochondrial monoamine oxidase MAO [AID125224, Type: Literature]
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46
[SID11114077]
Potency 15.8489qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6 [AID891, Type: confirmatory]cytochrome P450 2D6 isoform 1 [Homo sapiens] [gi:40805836]
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47
[SID26747166]
Potency 15.8489qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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48
[SID26747166]
Potency 15.8489qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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49
[SID103166710]
IC50 17Displacement of [3H]estradiol from human recombinant ERalpha [AID356892, Type: Literature]Estrogen receptor [gi:544257]
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50
[SID103166710]
IC50 17Displacement of [3H]estradiol from human recombinant ERalpha [AID356892, Type: Literature]Estrogen receptor [gi:544257]
View