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wogonin (CID 5281703) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(433)
 
 
Inconclusive(10)
 
 
Unspecified(27)
 
 
Top Targets:
7tm 4(30)
 
 
 
 
Peptidase C48(5)
 
 
 
CAP ED(4)
 
 
ABCC CFTR1(4)
 
 
RasGEF(4)
 
 
BioAssay Types:
Screening(266)
 
 
 
 
Confirmatory(157)
 
 
 
 
 
Literature(51)
 
 
 
 
BioActivity Types:
Potency(88)
 
 
 
 
 
IC50(17)
 
 
 
 
AC50(1)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 440    Data Row: 479   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103180235]
IC50 1.07Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassay [AID418268, Type: Literature]Prostaglandin G/H synthase 2 [gi:548483]
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2
[SID103180235]
IC50 1.08Evaluated for inhibition of COX-2 catalyzed PGE-2 production from LPS induced RAW 264.7 cells [AID166386, Type: Literature]
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3
[SID103180235]
Ki 2.04174Binding affinity towards benzodiazepine site in GABAA receptor [AID72729, Type: Literature]
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4
[SID103180235]
IC50 7.8Inhibition of iNOS-induced NO production in LPS-stimulated mouse BV2 cells after 24 hrs [AID654952, Type: Literature]Nitric oxide synthase, inducible [gi:266649]
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5
[SID85272354]
Potency 16.3601A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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6
[SID103180235]
IC50 39Antiinflammatory activity in PMA-stimulated human SW1353 cells assessed as inhibition of NF-kappaB activation [AID426206, Type: Literature]
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7
[SID103180235]
IC50 46Inhibition of COX2 [AID403340, Type: Literature]
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8
[SID85272354]
MLPCN PGC1a Modulators Measured in Cell-Based System Using Plate Reader - 2139-01_Activator_SinglePoint_HTS_Activity [AID651723, Type: screening]
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9
[SID85272354]
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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10
[SID103180235]
IC50 100Free radical scavenging activity of DPPH was determined [AID226689, Type: Literature]
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11
[SID103180235]
IC50 105Inhibition of trypsin-induced elevation in PAI1 production in HUVEC by ELISA [AID403947, Type: Literature]
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12
[SID103180235]
IC50 176.1Inhibition of cow milk xanthine oxidase [AID338975, Type: Literature]Xanthine dehydrogenase/oxidase [gi:109940048]
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13
[SID103180235]
IC50 350Displacement of [3H]LSD from human 5HT7 receptor expressed in CHO cells [AID355721, Type: Literature]5-hydroxytryptamine receptor 7 [gi:8488960]
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14
[SID85272354]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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15
[SID103180235]
Inhibition of electric eel AChE at 2 mg/ml by Ellman's method [AID697852, Type: Literature]Acetylcholinesterase [gi:14916521]
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16
[SID103180235]
Inhibition of horse BChE at 2 mg/ml by Ellman's method [AID697853, Type: Literature]Cholinesterase [gi:21362409]
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17
[SID103180235]
Estrogenic activity at ERalpha in human MVLN cells at 100 ug/mL after 24 hrs by luciferase reporter gene assay relative to E2 [AID642414, Type: Literature]Estrogen receptor [gi:544257]
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18
[SID103180235]
Estrogenic activity at ERalpha in human MVLN cells at 20 ug/mL after 24 hrs by luciferase reporter gene assay relative to E2 [AID642415, Type: Literature]Estrogen receptor [gi:544257]
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19
[SID103180235]
Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells at 10 uM by enzyme immunoassay [AID418267, Type: Literature]Prostaglandin G/H synthase 2 [gi:548483]
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20
[SID103180235]
Inhibition of Avian myeloblastosis virus reverse transcriptase [AID1084380, Type: other]Polyprotein II [gi:75651200]
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