myricetin (CID 5281672) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(266)
 
 
Inactive(705)
 
 
Inconclusive(127)
 
 
Unspecified(94)
 
 
Top Targets:
p450(26)
 
 
 
 
 
7TM GPCR Srx(19)
 
 
 
Pyr redox dim(14)
 
 
 
 
HELICc(11)
 
 
 
 
PLN02808(10)
 
 
BioAssay Types:
Confirmatory(593)
 
 
 
 
 
Screening(315)
 
 
 
 
Literature(172)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(441)
 
 
 
 
 
IC50(83)
 
 
 
 
EC50(11)
 
 
 
 
Ki(10)
 
 
 
AC50(4)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 903    Data Row: 1192   Total Pages: 24   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103258907]
Ki 0.027Inhibition of CYP1B1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufin [AID598342, Type: Literature]
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2
[SID103258907]
I50 0.035Inhibition of beef heart mitochondrial NADH oxidase assessed per mg of protein [AID338027, Type: other]
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3
[SID103258907]
I50 0.045Inhibition of beef heart mitochondrial succinoxidase assessed per mg of protein [AID338028, Type: other]
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4
[SID11111487]
Potency 0.1259qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta- Hydroxysteroid Dehydrogenase Type 10) Bound [gi:122921310]
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5
[SID56463598]
Potency 0.15qHTS Assay for the Inhibitors of L3MBTL1: Hit Validation [AID540279, Type: confirmatory]lethal(3)malignant brain tumor-like protein 1 isoform I [Homo sapiens] [gi:117938328]
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6
[SID56463598]
Potency 0.15qHTS Assay for the Inhibitors of L3MBTL1: Hit Validation [AID540279, Type: confirmatory]lethal(3)malignant brain tumor-like protein 1 isoform I [Homo sapiens] [gi:117938328]
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7
[SID11111488]
Potency 0.15qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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8
[SID11111488]
Potency 0.15qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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9
[SID11111488]
Potency 0.1585qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta- Hydroxysteroid Dehydrogenase Type 10) Bound [gi:122921310]
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10
[SID11111489]
Potency 0.1995qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta- Hydroxysteroid Dehydrogenase Type 10) Bound [gi:122921310]
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11
[SID50106561]
Potency 0.1995qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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12
[SID50106561]
Potency 0.1995qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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13
[SID103258907]
IC50 0.2Inhibition of beta amyloid (1 to 40) fibril formation [AID456194, Type: Literature]
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14
[SID103258907]
ID50 0.25Inhibition of Moloney murine leukemia virus reverse transcriptase using (riboadenylic acid)n(deoxythymidylic acid)12-18 as template primer by liquid scintillation counting [AID339056, Type: other]
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15
[SID103258907]
ID50 0.28Inhibition of Moloney murine leukemia virus reverse transcriptase using (ribocytidylic acid)n(deoxyguanylic acid)12-18 as template primer by liquid scintillation counting [AID339057, Type: other]
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16
[SID11111488]
Potency 0.2818qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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17
[SID124880771]
Potency 0.2818qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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18
[SID124880771]
Potency 0.2818qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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19
[SID103258907]
IC50 0.29Inhibition of beta amyloid (1 to 40) fibril formation by thioflavin T staining-based binding assay [AID456188, Type: Literature]
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20
[SID124880773]
Potency 0.2993qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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21
[SID124880773]
Potency 0.2993qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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22
[SID26753603]
Potency 0.3162qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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23
[SID26753604]
Potency 0.3162qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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24
[SID103258907]
IC50 0.33Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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25
[SID103258907]
IC50 0.34Inhibition of beta amyloid (1 to 42) fibril formation [AID456195, Type: Literature]
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26
[SID50106561]
Potency 0.3548qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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27
[SID50106561]
Potency 0.3548qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID1705, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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28
[SID103258907]
Ki 0.37Inhibition of CYP1A1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufin [AID598341, Type: Literature]
View
29
[SID103258907]
I50 0.37Inhibition of rat liver mitochondrial ATPase assessed per mg of protein [AID338025, Type: other]
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30
[SID50106561]
Potency 0.3981qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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31
[SID50106561]
Potency 0.3981qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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32
[SID103258907]
IC50 0.4Inhibition of beta amyloid (1 to 42) fibril formation by thioflavin T staining-based binding assay [AID456189, Type: Literature]
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33
[SID103258907]
IC50 0.4Inhibition of FabI [AID265759, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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34
[SID56463598]
Potency 0.4467qHTS Assay for the Inhibitors of L3MBTL1 [AID485360, Type: confirmatory]lethal(3)malignant brain tumor-like protein 1 isoform I [Homo sapiens] [gi:117938328]
View
35
[SID56463598]
Potency 0.4467qHTS Assay for the Inhibitors of L3MBTL1 [AID485360, Type: confirmatory]lethal(3)malignant brain tumor-like protein 1 isoform I [Homo sapiens] [gi:117938328]
View
36
[SID103258907]
IC50 0.56Inhibition of recombinant human His-tagged glyoxalase 1 expressed in Escherichia coli BL21 assessed as formation of S-D-lactoylglutathione after 5 mins by spectrophotometric method [AID626948, Type: Literature]Lactoylglutathione lyase [gi:134039205]
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37
[SID103258907]
IC50 0.56Inhibition of human recombinant His-tagged Glyoxalase 1 expressed in Sf21-Baculovirus system [AID381802, Type: Literature]Lactoylglutathione lyase [gi:134039205]
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38
[SID11111488]
Potency 0.5623qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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39
[SID103258907]
IC50 0.58Inhibition of Trypanosoma cruzi trans-Sialidase [AID634127, Type: Literature]
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40
[SID103258907]
IC50 0.6Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transfer [AID91426, Type: Literature]Integrase [gi:82312013]
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41
[SID56463598]
Potency 0.6506qHTS for inhibitors of Phosphogylcerate Kinase: Hit Validation Screen [AID686980, Type: confirmatory]phosphoglycerate kinase [Trypanosoma brucei] [gi:115503961]
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42
[SID50106561]
Potency 0.7079qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
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43
[SID50106561]
Potency 0.7079qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
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44
[SID103258907]
IC50 0.85Inhibition of GST-tagged Human papillomavirus 16 protein E6 interaction with His-tagged human caspase 8 expressed in Escherichia coli after 1 hr incubation followed by overnight incubation by Alpha screening technique [AID654746, Type: Literature]Protein E [gi:137757]
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45
[SID50106561]
Potency 0.8913qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2353, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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46
[SID50106561]
Potency 0.8913qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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47
[SID103258907]
IC50 0.9Inhibition of beta amyloid (1 to 40) fibril formation after 24 hrs by fluorimetry [AID456196, Type: Literature]
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48
[SID103258907]
IC50 0.92Inhibition of CK2 [AID378676, Type: Literature]
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49
[SID90341245]
Potency 0.9466qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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50
[SID90341245]
Potency 0.9466qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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