Bookmark and Share
3-methylquercetin (CID 5281654) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(19)
 
 
Inactive(73)
 
 
Inconclusive(13)
 
 
Unspecified(27)
 
 
Top Targets:
NR LBD ROR li..(4)
 
 
SLT beta(4)
 
 
 
Bromo ALL-1(4)
 
 
 
HELICc(4)
 
 
Menin(4)
 
 
 
BioAssay Types:
Confirmatory(61)
 
 
 
 
Literature(47)
 
 
 
 
 
Screening(24)
 
 
 
BioActivity Types:
Potency(61)
 
 
 
 
IC50(20)
 
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 101    Data Row: 132   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103489401]
IC50 0.017Inhibition of human CYP1B1 by EROD assay [AID502475, Type: Literature]Cytochrome P450 1B1 [gi:48429256]
View
2
[SID103489401]
IC50 0.056Inhibition of human CYP1A1 by EROD assay [AID502474, Type: Literature]Cytochrome P450 1A1 [gi:117139]
View
3
[SID103489401]
IC50 0.5Inhibition of CK2 assessed as level of ATP utilized by luciferase-based bioluminescence assay [AID353598, Type: Literature]
View
4
[SID103489401]
IC50 0.91Inhibition of CAMK2 assessed as level of ATP utilized by luciferase-based bioluminescence assay [AID353599, Type: Literature]
View
5
[SID103489401]
IC50 1.261Inhibition of human CYP1A2 by EROD assay [AID502473, Type: Literature]Cytochrome P450 1A2 [gi:117144]
View
6
[SID103489401]
IC50 2.51Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry [AID399340, Type: Literature]
View
7
[SID103489401]
IC50 2.75Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
View
8
[SID103489401]
IC50 3.8Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression after 18 hrs [AID400608, Type: Literature]
View
9
[SID103489401]
IC50 5Inhibition of FabI [AID265759, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
View
10
[SID103489401]
IC50 8.3Inhibition of FabG [AID265760, Type: Literature]3-oxoacyl-acyl-carrier protein reductase precursor [gi:75020671]
View
11
[SID103489401]
IC50 14.7Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum NF54 [AID265761, Type: Literature]
View
12
[SID85843252]
Luminescence Homogenous Primary HTS to Identify Inhibitors of STK33 Activity [AID2322, Type: screening]
View
13
[SID103489401]
Inhibition of heat-induced HSP70 expression in human Jurkat cells at 50 ug/mL treated for 1 hr before heat induction by Western blot [AID353590, Type: Literature]
View
14
[SID26756953]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View
15
[SID26756953]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View
16
[SID26756953]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
View
17
[SID26756953]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
View
18
[SID26756952]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View
19
[SID26756952]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
View
20
[SID103489401]
IC50 10Cytotoxicity against human HeLa cells by MTT assay [AID423636, Type: Literature]
View
21
[SID103489401]
CC50 50Cytotoxicity against human Huh7.5.1 cells by MTT assay [AID658255, Type: Literature]
View
22
[SID103489401]
IC50 88.6Inhibition of bovine liver NADH oxidase [AID354610, Type: Literature]
View
23
[SID103489401]
IC50 95Inhibition of pig kidney aldehyde reductase by spectrophotometry [AID354609, Type: Literature]
View
24
[SID103489401]
IC50 95Inhibition of pig lens aldose reductase by spectrophotometry [AID354608, Type: Literature]Aldose reductase [gi:584742]
View
25
[SID103489401]
IC50 160Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 5 mins prior to substrate addition measured after 35 mins by spectrophotocolorimetric assay [AID671261, Type: Literature]
View
26
[SID103489401]
IC50 160Inhibition of baker's yeast alpha-glucosidase [AID735123, Type: Literature]
View
27
[SID103489401]
Ki 1910Mixed type inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by Lineweaver-Burk plot and Dixon plot analysis [AID671262, Type: Literature]
View
28
[SID103489401]
Inhibition of oleic acid-induced triglyceride over-accumulation in human HepG2 cells incubated for 24 hrs relative to untreated control [AID690143, Type: Literature]
View
29
[SID103489401]
Antioxidant activity in human HepG2 cells assessed as reduction of oleic acid-induced ROS generation incubated for 24 hrs by DHCF-DA based fluorimetric assay relative to untreated control [AID690144, Type: Literature]
View
30
[SID103489401]
Cytotoxicity against human HepG2 cells incubated for 24 hrs by MTT assay [AID690145, Type: Literature]
View
31
[SID103489401]
Reducing activity assessed as chlorogenic acid equivalent per mmol standard at 37 degC for 30 mins by Folin-Ciocalteu reagent assay assay [AID690148, Type: Literature]
View
32
[SID103489401]
Reducing activity by cyclic voltammetry [AID690149, Type: Literature]
View
33
[SID103489401]
Inhibition of cell surface aminopeptidase N (APN/CD13) at 0.3*10e-3 M compound concentration [AID38382, Type: Literature]
View
34
[SID103489401]
Inhibition of neutral endopeptidase (NEP/CD13) at 0.3*10e-3 M compound concentration [AID147515, Type: Literature]
View
35
[SID26756953]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
36
[SID103489401]
Antiviral activity against HCV JFH-1 J399EM infected in Human Huh7.5.1 cells assessed as suppression of viral replication at 50 uM after 72 hrs by EGFP assay [AID658254, Type: Literature]
View
37
[SID103489401]
Antioxidant activity assessed as trolox equivalent by TEAC assay [AID456317, Type: Literature]
View
38
[SID103489401]
Antimutagenic activity in Salmonella Typhimurium TA98 assessed as inhibition of 3-nitrofluoranthene-induced mutation by Ames test [AID515157, Type: Literature]
View
39
[SID103489401]
Antioxidant activity assessed as DPPH free radical scavenging activity [AID616482, Type: Literature]
View
40
[SID103489401]
Inhibition of horse BChE at 2 mg/ml by Ellman's method [AID697853, Type: Literature]Cholinesterase [gi:21362409]
View
41
[SID103489401]
Inhibition of electric eel AChE at 2 mg/ml by Ellman's method [AID697852, Type: Literature]Acetylcholinesterase [gi:14916521]
View
42
[SID103489401]
Inhibition of cow milk xanthine oxidase at 50 ug/mL [AID338974, Type: Literature]Xanthine dehydrogenase/oxidase [gi:109940048]
View
43
[SID103489401]
Inhibition of thrombin in New Zealand rabbit plasma assessed as thrombin time at 100 uM after 3 mins by coagulometry [AID666768, Type: Literature]Thrombin [gi:75057499]
View
44
[SID103489401]
Inhibition of thrombin in New Zealand rabbit plasma assessed as prothrombin time at 100 uM by coagulometry [AID666769, Type: Literature]Thrombin [gi:75057499]
View
45
[SID103489401]
Inhibition of thrombin in New Zealand rabbit plasma assessed as activated partial thromboplastin time at 100 uM after 3 mins by coagulometry [AID666770, Type: Literature]Thrombin [gi:75057499]
View
46
[SID103489401]
Inhibition of thrombin in New Zealand rabbit plasma assessed as fibrinogen level at 100 uM by coagulometry [AID666771, Type: Literature]Thrombin [gi:75057499]
View
47
[SID26756953]
Potency Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
View
48
[SID85843252]
NSD2 Inhibitors Measured in Biochemical System Using Plate Reader - 2115-01_Inhibitor_SinglePoint_HTS_Activity [AID624260, Type: screening]histone-lysine N-methyltransferase NSD2 isoform 1 [Homo sapiens] [gi:109633019]
View
49
[SID103489401]
Inhibition of FabZ at 100 uM [AID265763, Type: Literature]Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) [gi:74844869]
View
50
[SID26756952]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View