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fisetin (CID 5281614) - Compound BioActivity Data
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BioActivity Outcomes:
Active(98)
 
 
Inactive(228)
 
 
Inconclusive(39)
 
 
Unspecified(82)
 
 
Top Targets:
p450(10)
 
 
 
 
GT1 Gtf like(8)
 
 
HSD10-like SD..(8)
 
 
KAT11(8)
 
 
 
PLDc mTdp1 2(6)
 
 
 
 
BioAssay Types:
Confirmatory(256)
 
 
 
 
Literature(135)
 
 
 
 
Screening(10)
 
 
 
BioActivity Types:
Potency(153)
 
 
 
 
IC50(41)
 
 
 
 
EC50(6)
 
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 337    Data Row: 447   Total Pages: 23   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103203131]
I50 0.015Inhibition of beef heart mitochondrial NADH oxidase assessed per mg of protein [AID338027, Type: Literature]
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2
[SID103203131]
I50 0.045Inhibition of beef heart mitochondrial succinoxidase assessed per mg of protein [AID338028, Type: Literature]
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3
[SID103203131]
IC50 0.2Inhibitory effect on the oxidative degradation of membrane lipids (lipid peroxidation assay) in microsomes of rat. [AID180466, Type: Literature]
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4
[SID103203131]
ID50 0.24Inhibition of Moloney murine leukemia virus reverse transcriptase using (ribocytidylic acid)n(deoxyguanylic acid)12-18 as template primer by liquid scintillation counting [AID339057, Type: Literature]
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5
[SID103203131]
ID50 0.28Inhibition of Moloney murine leukemia virus reverse transcriptase using (riboadenylic acid)n(deoxythymidylic acid)12-18 as template primer by liquid scintillation counting [AID339056, Type: Literature]
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6
[SID103203131]
IC50 0.35Inhibition of CK2 [AID378676, Type: Literature]
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7
[SID103203131]
IC50 0.35Inhibition of CK2 (unknown origin) [AID779050, Type: Literature]
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8
[SID124883072]
Potency 0.3981qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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9
[SID103203131]
IC50 0.42Inhibition of glycogen synthase kinase 3 [AID240981, Type: Literature]
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10
[SID103203131]
I50 0.48Inhibition of rat liver mitochondrial ATPase assessed per mg of protein [AID338025, Type: Literature]
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11
[SID124883071]
Potency 0.5623qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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12
[SID103203131]
IC50 0.57Inhibition of Cyclin-dependent kinase 5-p25nck5a [AID241232, Type: Literature]
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13
[SID103203131]
IC50 0.79Inhibition of cyclin-dependent kinase 1/cyclinB [AID241206, Type: Literature]
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14
[SID103203131]
IC50 0.85Inhibition of human cyclin-dependent kinase 6 complex with a virus-encoded cyclin from herpesvirus saimiri (Vcyclin) [AID242481, Type: Literature]Cyclin-dependent kinase 6 [gi:266423]
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15
[SID46393572]
IC50 0.85Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain B, Crystal Structure Of A Human Cyclin-Dependent Kinase 6 Complex With A Flavonol Inhibitor, Fisetin [gi:61680405]
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16
[SID46393572]
IC50 0.85Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain B, Crystal Structure Of A Human Cyclin-Dependent Kinase 6 Complex With A Flavonol Inhibitor, Fisetin [gi:61680405]
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17
[SID26749675]
Potency 0.8913Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2572, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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18
[SID103203131]
IC50 0.95Inhibition of 12-hLO [AID309798, Type: Literature]
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19
[SID103203131]
IC50 1Inhibition of Plasmodium falciparum FabI [AID494830, Type: Literature]
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20
[SID103203131]
IC50 1Inhibition of FabI [AID265759, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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