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Zearalenone (CID 5281576) - Compound BioActivity Data
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BioActivity Outcomes:
Active(174)
 
 
Inactive(1225)
 
 
Inconclusive(422)
 
 
Unspecified(46)
 
 
Top Targets:
NR LBD PPAR(35)
 
 
 
 
7TM GPCR Srx(25)
 
 
NR LBD ER(23)
 
 
 
 
NR LBD AR(20)
 
 
 
 
NR LBD TR(20)
 
 
 
 
BioAssay Types:
Confirmatory(720)
 
 
 
 
 
Screening(649)
 
 
 
 
 
Literature(63)
 
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(586)
 
 
 
 
 
IC50(68)
 
 
 
 
 
EC50(15)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1102    Data Row: 1867   Total Pages: 94   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17388663]
Potency 0.01qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID144208351]
Potency-Replicate_1 0.0133qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID144213818]
Potency-Replicate_1 0.0715qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID103592240]
EC50 0.11Agonist activity at ERbeta by fluorescence polarization assay [AID356007, Type: Literature]
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5
[SID144208351]
Ratio Potency (uM) 0.127982qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID144213818]
Ratio Potency (uM) 0.148106qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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7
[SID17388663]
Potency 0.3162qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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8
[SID17389683]
Potency 0.3981qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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9
[SID144208351]
Potency-Replicate_1 2.3439qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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10
[SID3714463]
IC50 2.402Tumor Hsp90 Inhibitors Dose Response Confirmation [AID712, Type: confirmatory]90-kda heat shock protein beta HSP90 beta [Homo sapiens] [gi:4261762]
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11
[SID3714463]
IC50 2.402Tumor Hsp90 Inhibitors Dose Response Confirmation [AID712, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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12
[SID144208351]
Ratio Potency (uM) 4.16811qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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13
[SID144213818]
Potency-Replicate_1 4.4731qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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14
[SID3714463]
EC50_uM 5.449Luminescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of Glycogen Synthase Kinase-3 beta Activity [AID434954, Type: confirmatory]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
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15
[SID144213818]
Ratio Potency (uM) 5.85159qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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16
[SID3714463]
IC50 6.922TR-FRET counterscreen for FAK inhibitors: dose-response biochemical high throughput screening assay to identify inhibitors of Proline-rich tyrosine kinase 2 (Pyk2) [AID1641, Type: confirmatory]PTK2B protein tyrosine kinase 2 beta [Homo sapiens] [gi:34784998]
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17
[SID144208351]
Potency-Replicate_1 9.3312qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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18
[SID144208351]
Ratio Potency (uM) 10.4698qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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19
[SID17388663]
Potency-Replicate_1 11.2202qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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20
[SID17389683]
Potency 11.2202qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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