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yangonin (CID 5281575) - Compound BioActivity Data
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BioActivity Outcomes:
Active(18)
 
 
Inactive(302)
 
 
Inconclusive(41)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD TR(9)
 
 
NR LBD AR(9)
 
 
 
NR LBD VDR(7)
 
 
BioAssay Types:
Confirmatory(311)
 
 
 
 
Summary(24)
 
 
 
 
Literature(8)
 
 
 
 
Screening(7)
 
 
 
BioActivity Types:
Potency(234)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 328    Data Row: 366   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209745]
Potency-Replicate_1 0.4429qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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2
[SID144209745]
Ratio Potency (uM) 0.557615qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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3
[SID144209745]
Potency-Replicate_1 0.8838qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID26753133]
Potency 1.7783qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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5
[SID17388664]
Potency 1.8834qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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6
[SID26753133]
Potency 8.9125qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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7
[SID17388664]
Potency 10qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway [AID651777, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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8
[SID144209745]
ATAD5 Potency (uM) 19.7849qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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9
[SID17388664]
Potency-Replicate_1 35.4813qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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10
[SID17388664]
Potency 50.1187qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
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11
[SID17388664]
Potency 66.8242qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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12
[SID17388664]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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13
[SID26753133]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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14
[SID26753133]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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15
[SID26753133]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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16
[SID26753133]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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17
[SID103752976]
Activation of Nrf2 in rat PC12 cells at 10 uM after 24 hrs by antioxidant response element-driven luciferase reporter gene assay [AID481210, Type: Literature]Nuclear factor erythroid 2-related factor 2 [gi:146345467]
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18
[SID103752976]
Induction of HO-1 protein expression in rat PC12 cells at 10 uM after 24 hrs by Western blot analysis [AID481211, Type: Literature]
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19
[SID103752976]
Inhibition of PA endonuclease at 10 uM [AID666150, Type: Literature]Polymerase acidic protein [gi:158931133]
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20
[SID103752976]
Inhibition of PA endonuclease at 1 uM [AID666151, Type: Literature]Polymerase acidic protein [gi:158931133]
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