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BioActivity Data for Compound mycophenolate mofetil (CID 5281078)

BioActivity Outcomes:
Active(43)
 
 
Inactive(71)
 
 
Inconclusive(28)
 
 
Unspecified(297)
 
 
Top Targets:
7tm 4(33)
 
 
 
p450(10)
 
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD AR(8)
 
 
 
 
 
NR LBD PPAR(8)
 
 
 
 
BioAssay Types:
Confirmatory(205)
 
 
 
 
 
Literature(35)
 
 
 
Summary(24)
 
 
 
 
Screening(15)
 
 
 
BioAssay Categories:
In vitro(1)
 
 
Biochemical(1)
 
 
Toxicity(28)
 
 
 
 
ADME(7)
 
 
 
Cell-based(31)
 
 
 
 
BioActivity Types:
IC50(131)
 
 
 
 
Potency(86)
 
 
 
 
AC50(6)
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 434    Data Row: 439   Total Pages: 22   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170464859]
IC50 0.001Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
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2
[SID170464859]
IC50 0.0147Increased HeLa cells in S-phase-IC50 [AID1117348, Type: confirmatory]
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3
[SID170464859]
IC50 0.0498GSK3B-pretreated HCT116 viability from Cell TiterGlo-IC50 [AID1117339, Type: confirmatory]
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4
[SID170464859]
IC50 0.0672HCT116 viability from Cell TiterGlo-IC50 [AID1117332, Type: confirmatory]
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5
[SID144205239]
Potency-Replicate_1 0.1059qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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6
[SID144205239]
Potency 0.1334qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID144205239]
Ratio Potency (uM) 0.141232qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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8
[SID170464859]
IC50 0.1648RKO viability from Cell TiterGlo-IC50 [AID1117322, Type: confirmatory]
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9
[SID144205239]
Potency 0.1679qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID144205239]
Ratio Potency (uM) 0.213138qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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11
[SID144205239]
Potency-Replicate_1 0.4216qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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12
[SID144205239]
Potency-Replicate_1 0.4216qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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13
[SID170464859]
Potency-Replicate_1 0.473qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743191, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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14
[SID144205239]
Potency-Replicate_1 0.5308qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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15
[SID144205239]
Potency-Replicate_1 0.674qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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16
[SID144205239]
Potency-Replicate_1 0.9439qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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17
[SID170464859]
Ratio Potency (uM) 1.05901qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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18
[SID144205239]
Potency 1.122qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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19
[SID144205239]
Potency 1.122qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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20
[SID170464859]
IC50 1.2605VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50 [AID1117337, Type: confirmatory]
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