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Oxymetholone (CID 5281034) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(70)
 
 
Inactive(267)
 
 
Inconclusive(275)
 
 
Unspecified(154)
 
 
Top Targets:
NR LBD PPAR(22)
 
 
 
NR LBD ER(18)
 
 
 
 
 
NR LBD AR(18)
 
 
 
 
7TM GPCR Srsx(17)
 
 
 
7TM GPCR Srx(17)
 
 
BioAssay Types:
Confirmatory(316)
 
 
 
 
Literature(81)
 
 
 
 
Summary(48)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(315)
 
 
 
 
IC50(116)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 424    Data Row: 766   Total Pages: 16   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144207269]
Potency-Replicate_1 0.0049qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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2
[SID144204682]
Potency-Replicate_1 0.0119qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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3
[SID17388810]
Potency 0.0708qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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4
[SID144207269]
Ratio Potency (uM) 0.0814027qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
5
[SID144207269]
Potency-Replicate_1 0.0978qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID144204682]
Ratio Potency (uM) 0.119856qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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7
[SID144204682]
Potency-Replicate_1 0.1199qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway [AID743036, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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8
[SID17388810]
Potency 0.1259qHTS assay for small molecule agonists of androgen receptor signaling [AID588515, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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9
[SID103770568]
IC50 0.206DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) [AID625228, Type: other]Androgen receptor [gi:113832]
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10
[SID144204682]
Potency-Replicate_1 0.2113qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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11
[SID17388810]
Potency 0.5623qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
12
[SID144204682]
Potency-Replicate_1 0.674qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
13
[SID144207269]
Potency-Replicate_1 0.7834qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
14
[SID144207269]
Ratio Potency (uM) 1.05199qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
15
[SID144204682]
Ratio Potency (uM) 1.24423qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
16
[SID144207269]
Ratio Potency (uM) 5.22391qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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17
[SID170465403]
Ratio Potency (uM) 6.30812qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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18
[SID144204682]
Potency 6.859qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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19
[SID17388810]
Potency 7.4978qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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20
[SID144204682]
Potency-Replicate_1 10.5909qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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21
[SID144204682]
Potency 11.8856qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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22
[SID144207269]
Potency-Replicate_1 15.496qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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23
[SID17388810]
Potency 15.8489qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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24
[SID17388810]
Potency 17.7828qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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25
[SID144204682]
Ratio Potency (uM) 18.9959qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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26
[SID144204682]
TR Potency (uM) 29.8493qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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27
[SID144204682]
Potency-Replicate_1 29.8493qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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28
[SID144204682]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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29
[SID144204682]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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30
[SID144207269]
Potency-Replicate_1 30.9185qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
31
[SID144207269]
Potency-Replicate_1 43.6735qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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32
[SID144207269]
Potency-Replicate_1 44.0526qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
View
33
[SID144207269]
Potency-Replicate_1 44.0526qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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34
[SID144207269]
Potency-Replicate_1 44.0526qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
View
35
[SID17388810]
Potency 44.6684qHTS assay for small molecule antagonists of androgen receptor signaling [AID588516, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
36
[SID144207269]
Potency-Replicate_1 49.0025qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
View
37
[SID144207269]
Potency-Replicate_1 49.0025qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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38
[SID144207269]
Potency-Replicate_1 49.4279qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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39
[SID144207269]
Potency-Replicate_1 49.4279qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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40
[SID144207269]
Potency-Replicate_1 49.4279qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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41
[SID144207269]
Potency-Replicate_1 49.4279qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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42
[SID144207269]
Potency-Replicate_1 49.4279qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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43
[SID17388810]
Potency 50.1187qHTS assay for cell viability of the p53RE-bla HCT-116 cell line [AID743292, Type: confirmatory]
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44
[SID17388810]
Potency 50.1187MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Dead Cells [AID946, Type: confirmatory]
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45
[SID17388810]
Potency 50.1187Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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46
[SID144207269]
Potency-Replicate_1 54.9817qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
47
[SID144207269]
AR Potency (uM) 54.9817qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
48
[SID144207269]
Potency-Replicate_1 55.459qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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49
[SID144207269]
Potency-Replicate_1 55.459qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
View
50
[SID144207269]
Ratio Potency (uM) 58.3706qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
View