Oxymetholone (CID 5281034) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(29)
 
 
Inactive(195)
 
 
Inconclusive(197)
 
 
Unspecified(154)
 
 
Top Targets:
7TM GPCR Srx(12)
 
 
7TM GPCR Srsx(10)
 
 
p450(10)
 
 
 
 
NR LBD PPAR(6)
 
 
 
P53(4)
 
 
 
BioAssay Types:
Confirmatory(174)
 
 
 
 
Literature(81)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(138)
 
 
 
 
IC50(116)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 329    Data Row: 575   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17388810]
Potency 0.0708qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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2
[SID17388810]
Potency 0.0708qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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3
[SID17388810]
Potency 0.1259qHTS assay for small molecule agonists of androgen receptor signaling [AID588515, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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4
[SID17388810]
Potency 0.1259qHTS assay for small molecule agonists of androgen receptor signaling [AID588515, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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5
[SID103770568]
IC50 0.206DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) [AID625228, Type: other]Androgen receptor [gi:113832]
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6
[SID103770568]
IC50 0.206DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) [AID625228, Type: other]Androgen receptor [gi:113832]
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7
[SID17388810]
Potency 0.5623qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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8
[SID17388810]
Potency 0.5623qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID17388810]
Potency 0.5623qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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10
[SID17388810]
Potency 0.5623qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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11
[SID144204682]
Potency 6.859qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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12
[SID144204682]
Potency 6.859qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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13
[SID144204682]
Potency 6.859qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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14
[SID144204682]
Potency 6.859qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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15
[SID17388810]
Potency 7.4978qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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16
[SID17388810]
Potency 7.4978qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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17
[SID17388810]
Potency 7.4978qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
View
18
[SID17388810]
Potency 7.4978qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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19
[SID144204682]
Potency 11.8856qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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20
[SID144204682]
Potency 11.8856qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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21
[SID144204682]
Potency 11.8856qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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22
[SID17388810]
Potency 15.8489qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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23
[SID17388810]
Potency 15.8489qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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24
[SID17388810]
Potency 15.8489qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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25
[SID17388810]
Potency 17.7828qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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26
[SID17388810]
Potency 44.6684qHTS assay for small molecule antagonists of androgen receptor signaling [AID588516, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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27
[SID17388810]
Potency 44.6684qHTS assay for small molecule antagonists of androgen receptor signaling [AID588516, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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28
[SID17388810]
Potency 50.1187MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Dead Cells [AID946, Type: confirmatory]
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29
[SID17388810]
Potency 50.1187Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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30
[SID17388810]
Potency 63.0957Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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31
[SID17388810]
 Cell Viability - Jurkat [AID426, Type: confirmatory]
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32
[SID17388810]
 Cell Viability - SH-SY5Y [AID544, Type: confirmatory]
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33
[SID17388810]
 Cell Viability - Renal Proximal Tubule [AID545, Type: confirmatory]
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34
[SID17388810]
 Cell Viability - NIH 3T3 [AID541, Type: confirmatory]
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35
[SID17388810]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_27, Type: other]
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36
[SID17388810]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_48, Type: other]
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37
[SID17388810]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_4, Type: other]
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38
[SID17388810]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_1, Type: other]
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39
[SID17388810]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_24, Type: other]
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40
[SID17388810]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_40, Type: other]
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41
[SID17388810]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_27, Type: other]
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42
[SID48414273]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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43
[SID48414273]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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44
[SID48414273]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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45
[SID17388810]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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46
[SID17388810]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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47
[SID144204682]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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48
[SID17388810]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
49
[SID17388810]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813, Type: other]
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50
[SID103770568]
IC50 DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) [AID625193, Type: other]Acetylcholinesterase [gi:113037]
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