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BioActivity Data for Compound Dacarbazine (CID 5281007)

BioActivity Outcomes:
Active(3)
 
 
Inactive(225)
 
 
Inconclusive(11)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
NR LBD Fxr(8)
 
 
 
NR LBD GR(8)
 
 
 
BioAssay Types:
Confirmatory(172)
 
 
 
 
 
Summary(58)
 
 
 
Screening(10)
 
 
 
BioAssay Categories:
Toxicity(12)
 
 
 
 
Cell-based(15)
 
 
 
BioActivity Types:
Potency(199)
 
 
 
 
AC50(12)
 
 
 
IC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 140    Data Row: 241   Total Pages: 13   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170464655]
IC50 4.5862VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50 [AID1117337, Type: confirmatory]
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2
[SID144208208]
Potency-Replicate_1 62.0019qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID170464655]
VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-screen [AID1117340, Type: screening]
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4
[SID170464655]
AC50 (uM) qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel [AID1117304, Type: confirmatory]
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5
[SID170464655]
AC50 (uM) qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel [AID1117305, Type: confirmatory]
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6
[SID174007370]
Potency 0.0013qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (HB3) proliferation [AID743347, Type: confirmatory]
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7
[SID174007370]
Potency 0.5952qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation (Rep 2) [AID743346, Type: confirmatory]
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8
[SID170464655]
Ac50 0.630957qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
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9
[SID170464655]
AC50 (uM) 0.631qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green channel [AID1117298, Type: confirmatory]
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10
[SID170464655]
Ac50 1qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, blue channel [AID1117311, Type: confirmatory]
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11
[SID170464655]
AC50 (uM) 1qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 1 blue channel [AID1117301, Type: confirmatory]
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12
[SID170464655]
Ac50 1.25893qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, ratio channel [AID1117318, Type: confirmatory]
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13
[SID170464655]
AC50 (uM) 1.26qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 1 ratio channel [AID1117303, Type: confirmatory]
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14
[SID170464655]
Ac50 1.77828qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, green channel [AID1117315, Type: confirmatory]
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15
[SID170464655]
AC50 (uM) 1.7783qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen1 green channel [AID1117302, Type: confirmatory]
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16
[SID170464655]
IC50 10Decreased HeLa cell count-IC50 [AID1117347, Type: confirmatory]
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17
[SID170464655]
IC50 10Increased HeLa cells in S-phase-IC50 [AID1117348, Type: confirmatory]
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18
[SID170464655]
IC50 10Increased HeLa cells with 2N DNA content-IC50 [AID1117349, Type: confirmatory]
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19
[SID170464655]
IC50 10Increased chromatin condensation in HeLa cells-IC50 [AID1117350, Type: confirmatory]
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20
[SID170464655]
IC50 10Increased HeLa cells with 4N DNA content-IC50 [AID1117351, Type: confirmatory]
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