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Dacarbazine (CID 5281007) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(172)
 
 
Inconclusive(10)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
NR LBD Fxr(8)
 
 
 
NR LBD VDR(8)
 
 
BioAssay Types:
Confirmatory(133)
 
 
 
 
Summary(48)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(169)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 97    Data Row: 183   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144208208]
Potency-Replicate_1 62.0019qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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2
[SID174007370]
Potency 0.0013qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (HB3) proliferation [AID743347, Type: confirmatory]
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3
[SID174007370]
Potency 0.5952qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation (Rep 2) [AID743346, Type: confirmatory]
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4
[SID174007370]
Potency 21.1177qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (3D7) proliferation [AID743344, Type: confirmatory]
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5
[SID174007370]
Potency 23.6945qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation [AID743345, Type: confirmatory]
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6
[SID144208208]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
View
7
[SID144204722]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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8
[SID144208208]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
9
[SID144204722]
AR Potency (uM) qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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10
[SID144204722]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
View
11
[SID144208208]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
View
12
[SID144204722]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
View
13
[SID144208208]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
View
14
[SID144204722]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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15
[SID144208208]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
16
[SID144204722]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
View
17
[SID144208208]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
View
18
[SID144204722]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
View
19
[SID144208208]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
View
20
[SID144204722]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
View