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BioActivity Data for Compound Dacarbazine (CID 5281007)

BioActivity Outcomes:
Active(3)
 
 
Inactive(191)
 
 
Inconclusive(10)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
NR LBD Fxr(8)
 
 
 
NR LBD GR(8)
 
 
 
BioAssay Types:
Confirmatory(146)
 
 
 
 
Summary(48)
 
 
 
Screening(10)
 
 
 
BioAssay Categories:
Toxicity(12)
 
 
 
 
Cell-based(15)
 
 
 
BioActivity Types:
Potency(169)
 
 
 
 
IC50(7)
 
 
 
AC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 118    Data Row: 204   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170464655]
IC50 4.5862VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50 [AID1117337, Type: confirmatory]
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2
[SID144208208]
Potency-Replicate_1 62.0019qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID170464655]
VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-screen [AID1117340, Type: screening]
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4
[SID174007370]
Potency 0.0013qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (HB3) proliferation [AID743347, Type: confirmatory]
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5
[SID174007370]
Potency 0.5952qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation (Rep 2) [AID743346, Type: confirmatory]
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6
[SID170464655]
Ac50 0.630957qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
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7
[SID170464655]
Ac50 1qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, blue channel [AID1117311, Type: confirmatory]
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8
[SID170464655]
Ac50 1.25893qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, ratio channel [AID1117318, Type: confirmatory]
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9
[SID170464655]
Ac50 1.77828qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, green channel [AID1117315, Type: confirmatory]
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10
[SID170464655]
IC50 10VEGF stimulated ADSC/ECFC co-culture nuclear area decrease (viability)-IC50 [AID1117324, Type: confirmatory]
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11
[SID170464655]
IC50 10Decreased HeLa cell count-IC50 [AID1117347, Type: confirmatory]
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12
[SID170464655]
IC50 10Increased HeLa cells in S-phase-IC50 [AID1117348, Type: confirmatory]
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13
[SID170464655]
IC50 10Increased HeLa cells with 2N DNA content-IC50 [AID1117349, Type: confirmatory]
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14
[SID170464655]
IC50 10Increased chromatin condensation in HeLa cells-IC50 [AID1117350, Type: confirmatory]
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15
[SID170464655]
IC50 10Increased HeLa cells with 4N DNA content-IC50 [AID1117351, Type: confirmatory]
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16
[SID174007370]
Potency 21.1177qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (3D7) proliferation [AID743344, Type: confirmatory]
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17
[SID174007370]
Potency 23.6945qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation [AID743345, Type: confirmatory]
View
18
[SID144208208]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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19
[SID144208208]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
20
[SID170464655]
GLP1 secretion from NCI-H716 cells-screen [AID1117341, Type: screening]
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