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gamma-Linolenic Acid (CID 5280933) - Compound BioActivity Data
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BioActivity Outcomes:
Active(25)
 
 
Inactive(653)
 
 
Inconclusive(34)
 
 
Unspecified(9)
 
 
Top Targets:
7tm 4(37)
 
 
NR LBD TR(9)
 
 
 
NR LBD ER(7)
 
 
PLDc mTdp1 2(7)
 
 
NR LBD AR(7)
 
 
BioAssay Types:
Screening(337)
 
 
 
Confirmatory(274)
 
 
 
 
 
Literature(87)
 
 
 
 
 
Summary(15)
 
 
 
BioActivity Types:
Potency(262)
 
 
 
 
 
IC50(22)
 
 
 
 
 
AC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 549    Data Row: 721   Total Pages: 37   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103636892]
IC50 0.27Inhibition of PPAR-alpha (unknown origin) by SPA assay [AID1094404, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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2
[SID103636892]
IC50 0.27Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay [AID1114584, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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3
[SID57260207]
AC50_uM 0.505VEID(2) R110 Enzymatic Primary HTS to identify Inhibitors of Caspase 6 Measured in Biochemical System Using Plate Reader - 7052-01_Inhibitor_Dose_CherryPick_Activity [AID720632, Type: confirmatory]Caspase 6, apoptosis-related cysteine peptidase [Homo sapiens] [gi:13325293]
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4
[SID103636892]
IC50 0.75Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay [AID1114582, Type: confirmatory]Peroxisome proliferator-activated receptor delta [gi:417522]
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5
[SID103636892]
IC50 2.2Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay [AID1114583, Type: confirmatory]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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6
[SID29216151]
Potency 14.1254qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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7
[SID57260207]
Potency 19.9526qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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8
[SID103636892]
IC50 20Inhibition of amidolytic activity of human recombinant soluble tissue factor/human factor 7a preincubated with factor 7a for 90 mins [AID402798, Type: Literature]
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9
[SID57260207]
Potency 21.1923qHTS for Inhibitors of Polymerase Kappa: Confirmatory Assay for Cherry-picked Compounds [AID720501, Type: Literature]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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10
[SID29216151]
Potency 23.7781qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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11
[SID57260207]
Potency 28.1838qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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12
[SID103636892]
IC50 30Inhibition of amidolytic activity of human tissue factor/human factor 7a [AID402795, Type: Literature]Tissue factor [gi:135666]
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13
[SID57260207]
Potency 30.1313qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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14
[SID29216151]
Potency 39.8107Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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15
[SID57260207]
Potency 39.8107qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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16
[SID103636892]
IC50 45Inhibition of amidolytic activity of human recombinant soluble tissue factor/human factor 7a preincubated with factor 7a for 15 mins [AID402797, Type: Literature]
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17
[SID57260207]
Potency 50.1187qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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18
[SID57260207]
Potency 67.0158qHTS for Inhibitors of Polymerase Iota: Confirmatory Assay for Cherry-picked Compounds [AID720496, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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19
[SID57260207]
Identification of Small Molecule Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Delta508 Mutation Function in Human Bronchial Epithelial Cells. Measured in Cell-Based System Using Plate Reader - 7017-01_Other_SinglePoint_HTS_Activity [AID720511, Type: screening]cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7 [Homo sapiens] [gi:89348172]
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20
[SID57260207]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463082, Type: screening]platelet-activating factor acetylhydrolase precursor [Homo sapiens] [gi:270133071]
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