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kaempferol (CID 5280863) - Compound BioActivity Data
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BioActivity Outcomes:
Active(167)
 
 
Inactive(876)
 
 
Inconclusive(146)
 
 
Unspecified(234)
 
 
Top Targets:
NR LBD PPAR(33)
 
 
 
 
 
p450(21)
 
 
 
 
NR LBD ER(20)
 
 
 
 
 
NR LBD AR(20)
 
 
 
 
 
NR LBD GR(18)
 
 
 
 
 
BioAssay Types:
Confirmatory(576)
 
 
 
 
 
Screening(365)
 
 
 
Literature(362)
 
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(501)
 
 
 
 
 
IC50(95)
 
 
 
 
 
EC50(9)
 
 
 
 
Ki(8)
 
 
 
Kd(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1104    Data Row: 1423   Total Pages: 72   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103206920]
IC50 0.028Inhibition of aryl hydrocarbon receptor [AID311070, Type: Literature]
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2
[SID103206920]
Ki 0.043Inhibition of CYP1B1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufin [AID598342, Type: Literature]
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3
[SID103206920]
IC50 0.047Inhibition of human CYP1B1 by EROD assay [AID502475, Type: Literature]Cytochrome P450 1B1 [gi:48429256]
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4
[SID144213678]
Potency-Replicate_1 0.3278qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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5
[SID103206920]
IC50 0.36Inhibition of human recombinant 17beta-HSD2 expressed in HEK293 cell lysate assessed as conversion of radiolabeled estrone to estradiol [AID406997, Type: Literature]Estradiol 17-beta-dehydrogenase 2 [gi:544152]
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6
[SID103206920]
IC50 0.632Inhibition of human CYP1A1 by EROD assay [AID502474, Type: Literature]Cytochrome P450 1A1 [gi:117139]
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7
[SID103206920]
IC50 0.716Inhibition of human CYP1A2 by EROD assay [AID502473, Type: Literature]Cytochrome P450 1A2 [gi:117144]
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8
[SID103206920]
Ki 0.75Inhibition of CYP1A1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufin [AID598341, Type: Literature]
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9
[SID103206920]
IC50 0.84Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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10
[SID103206920]
IC50 1.05Inhibition of human recombinant 17beta-HSD1 expressed in HEK293 cell lysate assessed as conversion of radiolabeled estrone to estradiol [AID406995, Type: Literature]Estradiol 17-beta-dehydrogenase 1 [gi:313104233]
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11
[SID103206920]
IC50 1.06Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry [AID399340, Type: Literature]
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12
[SID144213678]
Ratio Potency (uM) 1.16291qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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13
[SID103206920]
IC50 1.2Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay [AID510244, Type: Literature]
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14
[SID103206920]
ID50 1.22Inhibition of Moloney murine leukemia virus reverse transcriptase using (riboadenylic acid)n(deoxythymidylic acid)12-18 as template primer by liquid scintillation counting [AID339056, Type: Literature]
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15
[SID49674535]
AC50_uM 1.259MLPCN Dyrk1A Kinase Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_Dose_CherryPick_Activity [AID588345, Type: confirmatory]dual specificity tyrosine-phosphorylation-regulated kinase 1A [Rattus norvegicus] [gi:6978787]
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16
[SID103206920]
ID50 1.29Inhibition of Moloney murine leukemia virus reverse transcriptase using (ribocytidylic acid)n(deoxyguanylic acid)12-18 as template primer by liquid scintillation counting [AID339057, Type: Literature]
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17
[SID103206920]
IC50 1.33Inhibition of rat lens aldose reductase [AID385353, Type: Literature]Aldose reductase [gi:1168407]
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18
[SID11112381]
Potency 1.5849qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Homo sapiens] [gi:32879895]
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19
[SID103206920]
IC50 1.6Induction of mouse osteoclast apoptosis [AID311864, Type: Literature]
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20
[SID103206920]
IC50 1.7Inhibition of beta amyloid (1 to 40) fibril formation by thioflavin T staining-based binding assay [AID456188, Type: Literature]
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