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apigetrin (CID 5280704) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(19)
 
 
Unspecified(26)
 
 
Top Targets:
crotonase-lik..(1)
 
 
Chorismate bi..(1)
 
 
23DHB-AMP lg(1)
 
 
HTH MARR(1)
 
 
Sialidase(1)
 
 
BioAssay Types:
Literature(46)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
IC50(7)
 
 
 
 
EC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 56    Data Row: 56   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103582369]
GI50 0.076Growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program [AID247402, Type: Literature]
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2
[SID103582369]
EC50 12.3Cytoprotective activity against doxorubicin-induced cytotoxicity in rat H9c2 cells assessed as cell viability after 24 hrs by MTT assay [AID528046, Type: Literature]
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3
[SID103582369]
EC50 13.09Antioxidant activity assessed as ABTS radical scavenging activity [AID528045, Type: Literature]
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4
[SID103582369]
EC50 20.37Antioxidant activity of the compound assessed as DPPH radical scavenging activity after 30 mins [AID528043, Type: Literature]
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5
[SID103582369]
IC50 39.3Inhibition of Clostridium perfringens neuraminidase [AID455702, Type: Literature]Sialidase [gi:127825]
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6
[SID103582369]
IC50 46.9Noncompetitive inhibition of recombinant influenza A virus rvH1N1 A/Bervig_Mission/1/18 neuraminidase [AID455703, Type: Literature]
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7
[SID103582369]
Antiestrogenic activity in human MCF7 cells assessed as drug level causing inhibition of 100 pM E2-enhanced cell proliferation to level equivalent to 50 pM E2 after 96 hrs by alamar blue assay [AID470163, Type: Literature]
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8
[SID103582369]
Antiestrogenic activity in human MCF7 cells assessed as drug level causing inhibition of 100 pM E2-enhanced cell proliferation to level equivalent to 10 pM E2 after 96 hrs by alamar blue assay [AID470164, Type: Literature]
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9
[SID103582369]
Antiestrogenic activity in human T47D cells assessed as drug level causing inhibition of 100 pM E2-enhanced cell proliferation to level equivalent to 50 pM E2 after 96 hrs by alamar blue assay [AID470166, Type: Literature]
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10
[SID103582369]
Antiestrogenic activity in human T47D cells assessed as drug level causing inhibition of 100 pM E2-enhanced cell proliferation to level equivalent to 10 pM E2 after 96 hrs by alamar blue assay [AID470167, Type: Literature]
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11
[SID103582369]
Antiestrogenic activity in human T47D cells assessed as drug level causing inhibition of 100 pM E2-enhanced cell proliferation to level equivalent to 1 pM E2 after 96 hrs by alamar blue assay [AID470168, Type: Literature]
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12
[SID103582369]
IC50 20Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitrite accumulation after 24 hrs by Griess reagent method [AID469266, Type: Literature]
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13
[SID103582369]
EC50 61Antiviral activity against HIV1 3B infected in human H9 cells assessed as inhibition of viral replication after 3 days by p24 antigen capture assay [AID332929, Type: Literature]
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14
[SID103582369]
IC50 88.4Antioxidant activity assessed as inhibition of AAPH-induced hemolysis in rat RBC after 3 hrs [AID356014, Type: Literature]
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15
[SID103582369]
IC50 115Cytotoxicity against human H9 cells after 3 days [AID332930, Type: Literature]
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16
[SID103582369]
EC50 515100Antioxidant activity assessed as ferrous ion chelating activity [AID528044, Type: Literature]
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17
[SID103582369]
Antiestrogenic activity in human MCF7 cells assessed as drug level causing inhibition of 100 pM E2-enhanced cell proliferation to level equivalent to 1 pM E2 after 96 hrs by alamar blue assay [AID470165, Type: Literature]
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18
[SID103582369]
Antiestrogenic activity in human MCF7 cells assessed as inhibition of E2-enhanced cell proliferation at 0.1 to 100 uM after 96 hrs by alamar blue assay [AID470169, Type: Literature]
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19
[SID103582369]
Antimutagenic activity in Salmonella Typhimurium TA98 assessed as inhibition of 3-nitrofluoranthene-induced mutation by Ames test [AID515157, Type: Literature]
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20
[SID103582369]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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