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Hymecromone (CID 5280567) - Compound BioActivity Data
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BioActivity Outcomes:
Active(44)
 
 
Inactive(787)
 
 
Inconclusive(107)
 
 
Unspecified(116)
 
 
Top Targets:
7tm 4(30)
 
 
NR LBD PPAR(16)
 
 
 
 
GT1 Gtf like(15)
 
 
NR LBD AR(14)
 
 
 
 
NR LBD ER(14)
 
 
 
BioAssay Types:
Confirmatory(393)
 
 
 
 
 
Screening(370)
 
 
 
 
Literature(194)
 
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(322)
 
 
 
 
 
IC50(27)
 
 
 
 
Ki(4)
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 831    Data Row: 1054   Total Pages: 53   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103173444]
Ki 0.56Inhibition of human recombinant CA9 after 6 hrs by stopped flow CO2 hydration assay [AID641825, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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2
[SID103173444]
IC50 1Inhibition of human 17beta-HSD3 expressed in HeLa cells [AID452459, Type: Literature]Testosterone 17-beta-dehydrogenase 3 [gi:1169300]
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3
[SID11112236]
Potency 2.5119qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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4
[SID11112236]
Potency 2.5119qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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5
[SID103173444]
Ki 8.1Inhibition of human recombinant CA12 after 6 hrs by stopped flow CO2 hydration assay [AID641826, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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6
[SID144203936]
Potency-Replicate_1 10qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture [AID720681, Type: confirmatory]
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7
[SID144203936]
Potency-Replicate_1 10qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cell free culture [AID720685, Type: confirmatory]
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8
[SID144203936]
Potency-Replicate_1 10qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells [AID720687, Type: confirmatory]
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9
[SID11112236]
Potency 10qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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10
[SID11112236]
Potency 10qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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11
[SID144203936]
Potency-Replicate_1 11.2202qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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12
[SID170465819]
Potency-Replicate_1 21.13qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway [AID743222, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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13
[SID103173444]
IC50 24.5Inhibition human recombinant aldose reductase 1 by spectrophotometric analysis [AID516862, Type: Literature]Aldose reductase [gi:113596]
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14
[SID170465819]
Potency-Replicate_1 26.6011qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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15
[SID144211232]
Potency-Replicate_1 30.6379qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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16
[SID144211232]
Potency-Replicate_1 39.8107qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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17
[SID144211232]
Potency-Replicate_1 39.8107qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cell free culture [AID720685, Type: confirmatory]
View
18
[SID144211232]
Potency-Replicate_1 39.8107qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture [AID720681, Type: confirmatory]
View
19
[SID144211232]
Potency-Replicate_1 39.8107qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells [AID720687, Type: confirmatory]
View
20
[SID144211232]
Potency-Replicate_1 43.6412qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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