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retinol palmitate (CID 5280531) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(656)
 
 
Inconclusive(41)
 
 
Unspecified(18)
 
 
Top Targets:
7tm 4(37)
 
 
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
 
NR LBD PPAR(10)
 
 
NR LBD GR(8)
 
 
 
BioAssay Types:
Screening(316)
 
 
 
 
Confirmatory(295)
 
 
 
 
Summary(39)
 
 
 
 
Literature(19)
 
 
 
BioActivity Types:
Potency(311)
 
 
 
 
 
IC50(10)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 596    Data Row: 722   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213325]
Ratio Potency (uM) 17.2289qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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2
[SID57260141]
uHTS identification of small molecule inhibitors of tim10-1 yeast via a luminescent assay [AID463190, Type: screening]TPA: protein transporter TIM10 [Saccharomyces cerevisiae S288c] [gi:285809906]
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3
[SID8150002]
Suppression of Polyglutamine Toxicity in Whole Organism Drosophila Model of SCA1 (SCA1FLYp) [AID1597, Type: other]
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4
[SID57260141]
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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5
[SID57260141]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463082, Type: screening]platelet-activating factor acetylhydrolase precursor [Homo sapiens] [gi:270133071]
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6
[SID8150002]
Suppression of Polyglutamine Toxicity in Whole Organism Drosophila Model of SCA1 (SCA1FLYe) [AID1595, Type: other]
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7
[SID57260141]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
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8
[SID103641027]
Induction of CRABP 2 mRNA expression in human normal fibroblast at 1 uM by Western blot relative to control [AID404775, Type: Literature]
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9
[SID103641027]
Induction of CRABP 2 mRNA expression in human normal fibroblast at 10 uM by Western blot relative to control [AID404776, Type: Literature]
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10
[SID57260141]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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11
[SID8150002]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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12
[SID8150002]
Screen for compounds that correct neuronal dysfunction without cell death as induced by the expression of polyglutamine-expanded, N-terminal huntingtin in C. elegans mechanosensory neurons (HDELENEU) [AID1599, Type: other]
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13
[SID8150002]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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14
[SID8150002]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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15
[SID8150002]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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16
[SID8150002]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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17
[SID8150002]
Screen for compounds that induce the human heat shock transcriptional response (HSEluc) [AID1611, Type: other]
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18
[SID8150002]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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19
[SID8150002]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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20
[SID8150002]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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