Bookmark and Share
beta Carotene (CID 5280489) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(15)
 
 
Inactive(358)
 
 
Inconclusive(30)
 
 
Unspecified(182)
 
 
Top Targets:
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
HCV capsid(5)
 
 
 
NR LBD TR(5)
 
 
7tm 4(5)
 
 
BioAssay Types:
Literature(240)
 
 
 
 
 
Confirmatory(145)
 
 
 
 
Screening(133)
 
 
 
 
Summary(15)
 
 
BioActivity Types:
Potency(139)
 
 
 
 
IC50(16)
 
 
 
Ki(2)
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 514    Data Row: 585   Total Pages: 30   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103401011]
IC50 0.0127Inhibition of TPA-induced Epstein-Barr virus early antigen activation in Raji cells after 48 hrs [AID288764, Type: Literature]
View
2
[SID103401011]
Ki 0.34Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977601, Type: Literature]
View
3
[SID103401011]
IC50 0.6166pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977600, Type: Literature]
View
4
[SID103401011]
Ki 2.26Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977604, Type: Literature]
View
5
[SID103401011]
IC50 2.95121pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977603, Type: Literature]
View
6
[SID103401011]
EC50 6.3Antiviral activity against HCV assessed as inhibition of HCV RNA replication in OR6 cells after 72 hrs by luciferase reporter assay [AID323922, Type: Literature]
View
7
[SID103401011]
IC50 16.9Antioxidant activity assessed as hydrogen peroxide scavenging activity by peroxyoxalate chemiluminescent method [AID452853, Type: Literature]
View
8
[SID103401011]
Antiradical activity assessed as DPPH radical scavenging activity at 1050 uM by spectrophotometry relative to control [AID378050, Type: Literature]
View
9
[SID47193664]
Heat Shock Factor-1 (HSF-1) Measured in Cell-Based System Using Plate Reader - 2038-01_Activator_SinglePoint_HTS_Activity [AID504408, Type: screening]
View
10
[SID48413385]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
View
11
[SID48415624]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
View
12
[SID103401011]
Antiviral activity against HCV assessed as suppression of HCV RNA replication in ORN/C-5B/KE/poly cells after 72 hrs by luciferase reporter assay [AID323924, Type: Literature]
View
13
[SID103401011]
Antiviral activity against HCV assessed as suppression of HCV RNA replication in ORN/3-5B/KE/poly cells after 72 hrs by luciferase reporter assay [AID323925, Type: Literature]
View
14
[SID103401011]
Antiviral activity against HCV assessed as inhibition of HCV RNA replication in OR6 cells after 24 hrs by luciferase reporter assay [AID323928, Type: Literature]
View
15
[SID47193664]
TR-FRET-based primary biochemical high-throughput screening assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization [AID1899, Type: screening]core protein, partial [Hepatitis C virus] [gi:83779224]
View
16
[SID103401011]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
View
17
[SID103401011]
Antioxidant activity assessed as formazan formation induced absorbance changes at 25 ppm at 570 nm at 37 degC for 6 hrs by MTT assay [AID492140, Type: Literature]
View
18
[SID103401011]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
View
19
[SID26750098]
Potency qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
20
[SID103401011]
Cytotoxicity against human OR6 cells after 72 hrs [AID323929, Type: Literature]
View