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beta Carotene (CID 5280489) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(356)
 
 
Inconclusive(31)
 
 
Unspecified(180)
 
 
Top Targets:
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
TRP 2(5)
 
 
HCV capsid(5)
 
 
 
NR LBD TR(5)
 
 
BioAssay Types:
Literature(234)
 
 
 
 
 
Confirmatory(144)
 
 
 
 
Screening(133)
 
 
 
 
Summary(15)
 
 
BioActivity Types:
Potency(138)
 
 
 
 
IC50(14)
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 507    Data Row: 578   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103401011]
IC50 0.0127Inhibition of TPA-induced Epstein-Barr virus early antigen activation in Raji cells after 48 hrs [AID288764, Type: Literature]
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2
[SID103401011]
EC50 6.3Antiviral activity against HCV assessed as inhibition of HCV RNA replication in OR6 cells after 72 hrs by luciferase reporter assay [AID323922, Type: Literature]
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3
[SID103401011]
IC50 16.9Antioxidant activity assessed as hydrogen peroxide scavenging activity by peroxyoxalate chemiluminescent method [AID452853, Type: Literature]
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4
[SID48413385]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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5
[SID48415624]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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6
[SID103401011]
Antiradical activity assessed as DPPH radical scavenging activity at 1050 uM by spectrophotometry relative to control [AID378050, Type: Literature]
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7
[SID103401011]
Antiviral activity against HCV assessed as suppression of HCV RNA replication in ORN/C-5B/KE/poly cells after 72 hrs by luciferase reporter assay [AID323924, Type: Literature]
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8
[SID103401011]
Antiviral activity against HCV assessed as suppression of HCV RNA replication in ORN/3-5B/KE/poly cells after 72 hrs by luciferase reporter assay [AID323925, Type: Literature]
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9
[SID103401011]
Antiviral activity against HCV assessed as inhibition of HCV RNA replication in OR6 cells after 24 hrs by luciferase reporter assay [AID323928, Type: Literature]
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10
[SID47193664]
TR-FRET-based primary biochemical high-throughput screening assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization [AID1899, Type: screening]core protein [Hepatitis C virus] [gi:83779224]
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11
[SID47193664]
Heat Shock Factor-1 (HSF-1) Measured in Cell-Based System Using Plate Reader - 2038-01_Activator_SinglePoint_HTS_Activity [AID504408, Type: screening]
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12
[SID26750098]
Potency qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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13
[SID103401011]
Cytotoxicity against human OR6 cells after 72 hrs [AID323929, Type: Literature]
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14
[SID103401011]
Cytotoxicity against human OR6 cells after 120 hrs [AID323932, Type: Literature]
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15
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 1000 molar ratio after 48 hrs relative to TPA [AID332212, Type: Literature]
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16
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 500 molar ratio after 48 hrs relative to TPA [AID332213, Type: Literature]
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17
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 100 molar ratio after 48 hrs relative to TPA [AID332214, Type: Literature]
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18
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 10 molar ratio after 48 hrs relative to TPA [AID332215, Type: Literature]
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19
[SID103401011]
Cytotoxicity against human Raji cells assessed as cell viability at 1000 molar ratio after 48 hrs by trypan blue assay [AID332216, Type: Literature]
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20
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 1000 molar ratio after 48 hrs relative to TPA [AID332228, Type: Literature]
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21
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 500 molar ratio after 48 hrs relative to TPA [AID332229, Type: Literature]
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22
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 100 molar ratio after 48 hrs relative to TPA [AID332230, Type: Literature]
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23
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 10 molar ratio after 48 hrs relative to TPA [AID332231, Type: Literature]
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24
[SID103401011]
Cytotoxicity against human Raji cells assessed as cell viability at 1000 molar ratio after 48 hrs by trypan blue assay [AID332232, Type: Literature]
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25
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 32 nM after 48 hrs relative to control [AID333230, Type: Literature]
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26
[SID103401011]
Cytotoxicity against human Raji cells at 32 nM after 48 hrs by trypan blue staining method [AID333231, Type: Literature]
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27
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 16 nM after 48 hrs relative to control [AID333232, Type: Literature]
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28
[SID103401011]
Cytotoxicity against human Raji cells at 16 nM after 48 hrs by trypan blue staining method [AID333233, Type: Literature]
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29
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 3.2 nM after 48 hrs relative to control [AID333234, Type: Literature]
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30
[SID103401011]
Cytotoxicity against human Raji cells at 3.2 nM after 48 hrs by trypan blue staining method [AID333235, Type: Literature]
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31
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 0.32 nM after 48 hrs relative to control [AID333236, Type: Literature]
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32
[SID103401011]
Cytotoxicity against human Raji cells at 0.32 nM after 48 hrs by trypan blue staining method [AID333237, Type: Literature]
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33
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed as early antigen activation at 32 nmol after 48 hrs relative to control [AID336754, Type: Literature]
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34
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed as early antigen activation at 16 nmol after 48 hrs relative to control [AID336755, Type: Literature]
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35
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed as early antigen activation at 3.2 nmol after 48 hrs relative to control [AID336756, Type: Literature]
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36
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed as early antigen activation at 0.32 nmol after 48 hrs relative to control [AID336757, Type: Literature]
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37
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed as early antigen activation after 48 hrs relative to control [AID336758, Type: Literature]
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38
[SID103401011]
Cytotoxicity against human Raji cells assessed as cell viability at 32 nmol after 48 hrs by tryan blue staining [AID336759, Type: Literature]
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39
[SID103401011]
Cytotoxicity against human Raji cells assessed as cell viability at 16 nmol after 48 hrs by tryan blue staining [AID336760, Type: Literature]
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40
[SID103401011]
Cytotoxicity against human Raji cells assessed as cell viability at 3.2 nmol after 48 hrs by tryan blue staining [AID336761, Type: Literature]
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41
[SID103401011]
Cytotoxicity against human Raji cells assessed as cell viability at 0.32 nmol after 48 hrs by tryan blue staining [AID336762, Type: Literature]
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42
[SID103401011]
Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced EBV-early antigen activation in human Raji cells assessed as EA activation at 1000 molar ratio after 48 hrs by indirect immunofluorescence method relative to TPA [AID338907, Type: Literature]
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43
[SID103401011]
Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced EBV-early antigen activation in human Raji cells assessed as EA activation at 500 molar ratio after 48 hrs by indirect immunofluorescence method relative to TPA [AID338908, Type: Literature]
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44
[SID103401011]
Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced EBV-early antigen activation in human Raji cells assessed as EA activation at 100 molar ratio after 48 hrs by indirect immunofluorescence method relative to TPA [AID338909, Type: Literature]
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45
[SID103401011]
Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced EBV-early antigen activation in human Raji cells assessed as EA activation at 10 molar ratio after 48 hrs by indirect immunofluorescence method relative to TPA [AID338910, Type: Literature]
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46
[SID103401011]
Cytotoxicity against human Raji cells assessed as cell viability at 1000 molar ratio [AID338911, Type: Literature]
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47
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 32 nmol after 48 hrs relative to TPA [AID354407, Type: Literature]
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48
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 16 nmol after 48 hrs relative to TPA [AID354408, Type: Literature]
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49
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 3.2 nmol after 48 hrs relative to TPA [AID354409, Type: Literature]
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50
[SID103401011]
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells at 0.32 nmol after 48 hrs relative to TPA [AID354410, Type: Literature]
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