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quercitrin (CID 5280459) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(30)
 
 
Inactive(396)
 
 
Inconclusive(7)
 
 
Unspecified(46)
 
 
Top Targets:
7TM GPCR Srx(14)
 
 
7TM GPCR Srsx(13)
 
 
 
alkPPc(6)
 
 
 
Aldo ket red(5)
 
 
RasGEF(4)
 
 
BioAssay Types:
Screening(305)
 
 
 
Confirmatory(101)
 
 
 
 
 
Literature(67)
 
 
 
 
BioActivity Types:
Potency(87)
 
 
 
 
 
IC50(28)
 
 
 
 
 
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 444    Data Row: 479   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103284478]
IC50 0.15Inhibition of human recombinant aldose reductase [AID322413, Type: Literature]Aldose reductase [gi:113596]
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2
[SID103284478]
IC50 0.16Inhibition of rat lens aldose reductase [AID385353, Type: Literature]Aldose reductase [gi:1168407]
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3
[SID103284478]
IC50 2Inhibition of human recombinant aldose reductase using D-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured for every 10 secs for 50 mins by spectrophotometry [AID639825, Type: Literature]Aldose reductase [gi:113596]
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4
[SID85149171]
AC50_uM 2.48Turbidometric Biochemical Primary HTS to identify inhibitors of Protein Disulfide Isomerase Measured in Biochemical System Using Plate Reader - 2137-01_Inhibitor_Dose_CherryPick_Activity [AID602350, Type: confirmatory]Prolyl 4-hydroxylase, beta polypeptide [Homo sapiens] [gi:14790033]
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5
[SID85149171]
AC50_uM 2.48Turbidometric Biochemical Primary HTS to identify inhibitors of Protein Disulfide Isomerase Measured in Biochemical System Using Plate Reader - 2137-01_Inhibitor_Dose_CherryPick_Activity_Set2 [AID624274, Type: confirmatory]Prolyl 4-hydroxylase, beta polypeptide [Homo sapiens] [gi:14790033]
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6
[SID103284478]
IC50 8.1Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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7
[SID103284478]
IC50 9Antialgal activity against Microcystis aeruginosa NIES 44 after 24 hrs by fluorophotometric method [AID337227, Type: other]
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8
[SID103284478]
IC50 10In vitro inhibition of partially purified calf lens aldose reductase; value ranges from 10E-5 to 10E-6 [AID34503, Type: Literature]Aldose reductase [gi:113594]
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9
[SID103284478]
IC50 12.46Inhibition of human RNase H by FRET assay [AID362726, Type: Literature]
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10
[SID103284478]
IC50 14.74Inhibition of xanthine oxidase-mediated formation of uric acid by spectrophotometry [AID336485, Type: Literature]
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11
[SID103284478]
IC50 21.27Inhibition of HIV2 RNase H by FRET assay [AID362724, Type: Literature]
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12
[SID103284478]
IC50 25Inhibition of Pim2 kinase [AID327000, Type: Literature]
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13
[SID85149171]
AC50_uM 29.77Luminescence Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of GSK-3 alpha [AID463203, Type: confirmatory]glycogen synthase kinase-3 alpha [Homo sapiens] [gi:49574532]
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14
[SID103284478]
IC50 33.3Inhibition of mouse recombinant AKR1C21 [AID322409, Type: Literature]Aldo-keto reductase family 1 member C21 [gi:172045824]
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15
[SID85149171]
Potency 35.4813qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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16
[SID85149171]
Potency 44.6684qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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17
[SID103284478]
IC50 45Antialgal activity against Anabaena flos-aquae NIES 73 after 48 hrs by fluorophotometric method [AID337228, Type: other]
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18
[SID103284478]
Cytotoxicity against african green monkey Vero cells after 3 days by MTT assay [AID469284, Type: Literature]
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19
[SID103284478]
Growth inhibition of BALB/c mouse cloned 3T3/A31 cells at 100 ug/mL after 72 hrs by nigrosin assay [AID379093, Type: Literature]
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20
[SID103284478]
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS/IFN-gamma-induced NO production at 25 to 100 uM after 20 hrs by Griess method [AID646459, Type: Literature]
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21
[SID85149171]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]integrase [Human immunodeficiency virus 1] [gi:2853980]
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22
[SID85149171]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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23
[SID85149171]
Turbidometric Biochemical Primary HTS to identify inhibitors of Protein Disulfide Isomerase Measured in Biochemical System Using Plate Reader - 2137-01_Inhibitor_SinglePoint_HTS_Activity [AID588391, Type: screening]Prolyl 4-hydroxylase, beta polypeptide [Homo sapiens] [gi:14790033]
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24
[SID85149171]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1B, catalytic subunit 3 (PAFAH1B3) [AID492972, Type: screening]platelet-activating factor acetylhydrolase IB subunit gamma [Homo sapiens] [gi:225543099]
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25
[SID85149171]
HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_SinglePoint_HTS [AID485317, Type: screening]FAD-linked sulfhydryl oxidase ALR [Homo sapiens] [gi:54112432]
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26
[SID85149171]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl) [AID588664, Type: screening]tyrosine-protein kinase ABL1 isoform a [Homo sapiens] [gi:62362414]
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27
[SID85149171]
TRFRET-based biochemical high throughput confirmation assay for inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl) [AID602124, Type: screening]tyrosine-protein kinase ABL1 isoform a [Homo sapiens] [gi:62362414]
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28
[SID85149171]
uHTS Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase [AID2544, Type: screening]Alkaline phosphatase, intestinal [Homo sapiens] [gi:124376142]
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29
[SID85149171]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl) [AID588664, Type: screening]ras and Rab interactor 1 [Homo sapiens] [gi:68989256]
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30
[SID85149171]
TRFRET-based biochemical high throughput confirmation assay for inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl) [AID602124, Type: screening]ras and Rab interactor 1 [Homo sapiens] [gi:68989256]
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31
[SID103284478]
IC50 0.1In vitro inhibitory activity towards partially purified rat lens aldose reductase [AID34809, Type: Literature]
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32
[SID103284478]
IC50 22.3Inhibition of HIV1 RNase H by FRET assay [AID362723, Type: Literature]
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33
[SID103284478]
IC50 100Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry [AID399340, Type: Literature]
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34
[SID103284478]
IC50 223Growth inhibition of BALB/c mouse cloned 3T3/A31 cells after 72 hrs by nigrosin assay [AID379089, Type: Literature]
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35
[SID103284478]
IC50 2000Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 mins [AID399405, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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36
[SID103284478]
IC50 2000Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production [AID399402, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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37
[SID103284478]
IC50 2000Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 mins [AID399404, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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38
[SID103284478]
IC50 2000Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production [AID399401, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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39
[SID103284478]
Displacement of [3H]DPCPX from adenosine A1 receptor in rat forebrain membrane assessed as fraction of receptor bound radioligand at 100 ug/mL [AID403918, Type: Literature]Adenosine receptor A1 [gi:2827766]
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40
[SID103284478]
Inhibition of electric eel AChE at 2 mg/ml by Ellman's method [AID697852, Type: Literature]Acetylcholinesterase [gi:14916521]
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41
[SID103284478]
Inhibition of horse BChE at 2 mg/ml by Ellman's method [AID697853, Type: Literature]Cholinesterase [gi:21362409]
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42
[SID103284478]
Stimulation of BALB/c mouse cloned 3T3/A31 cells growth at 0.01 to 1 ug/mL [AID379095, Type: Literature]
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43
[SID103284478]
Inhibition of Saccharomyces cerevisiae FAS [AID355748, Type: Literature]
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44
[SID103284478]
Antidepressant activity in rat assessed as immobility time at 0.6 mg/kg, po by forced swimming test (Rvb = 150.3 +/- 11.1 sec) [AID478692, Type: Literature]
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45
[SID103284478]
Antidepressant activity in rat assessed as immobility time at 1.3 mg/kg, po by forced swimming test (Rvb = 150.3 +/- 11.1 sec) [AID478693, Type: Literature]
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46
[SID103284478]
Antioxidant activity assessed as formazan formation induced absorbance changes at 25 ppm at 570 nm at 37 degC for 6 hrs by MTT assay [AID492140, Type: Literature]
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47
[SID103284478]
Inhibition of HIV1 recombinant integrase expressed in Escherichia coli [AID399391, Type: Literature]
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48
[SID85149171]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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49
[SID103284478]
Cytotoxic activity against KB 3-1 cells at 5 ug/mL. [AID95334, Type: Literature]
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50
[SID103284478]
Antimalarial potency against Plasmodium falciparum at 0.05 ng/mL. [AID160027, Type: Literature]
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