Bookmark and Share
Linoleic Acid (CID 5280450) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(38)
 
 
Inactive(535)
 
 
Inconclusive(88)
 
 
Unspecified(62)
 
 
Top Targets:
NR LBD PPAR(29)
 
 
 
 
 
NR LBD ER(27)
 
 
 
 
NR LBD AR(25)
 
 
 
NR LBD TR(21)
 
 
 
 
NR LBD GR(16)
 
 
 
 
BioAssay Types:
Confirmatory(459)
 
 
 
 
Literature(163)
 
 
 
 
 
Summary(63)
 
 
 
 
Screening(15)
 
 
BioActivity Types:
Potency(463)
 
 
 
 
IC50(26)
 
 
 
 
EC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 397    Data Row: 723   Total Pages: 37   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17388946]
Potency 0.1585qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
View
2
[SID103167732]
EC50 0.54Agonist activity at human GPR40 expressed in CHOK1 cells by fluorescence assay [AID371576, Type: Literature]Free fatty acid receptor 1 [gi:3122157]
View
3
[SID103167732]
EC50 0.54Agonist activity at GPR40 [AID371570, Type: Literature]
View
4
[SID103167732]
IC50 1Displacement of 8-anilino-1-naphthalene-sulfonic acid from human His-FABP4 expressed in Escherichia coli BL21 (DE3) cells after 3 mins relative to linoleic acid [AID483950, Type: Literature]Fatty acid-binding protein, adipocyte [gi:119781]
View
5
[SID103167732]
IC50 1Displacement of 8-anilino-1-naphthalene-sulfonic acid from human His-FABP3 expressed in Escherichia coli BL21 (DE3) cells after 3 mins relative to linoleic acid [AID483948, Type: Literature]Fatty acid-binding protein, heart [gi:119802]
View
6
[SID103167732]
IC50 1Allosteric inhibition of soybean LO1 [AID455080, Type: Literature]Seed linoleate 13S-lipoxygenase-1 [gi:126398]
View
7
[SID103167732]
EC50 1.8Agonist activity at human GPR40 expressed in CHO cells assessed as calcium flux by FLIPR assay [AID371573, Type: Literature]Free fatty acid receptor 1 [gi:3122157]
View
8
[SID17388946]
Potency 8.9125qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
View
9
[SID103167732]
IC50 11Competitive inhibition of soybean LO1 [AID455078, Type: Literature]Seed linoleate 13S-lipoxygenase-1 [gi:126398]
View
10
[SID103167732]
IC50 13Mixed-type inhibition of soybean LO1 [AID455079, Type: Literature]Seed linoleate 13S-lipoxygenase-1 [gi:126398]
View
11
[SID103167732]
IC50 13Inhibition of COX1 [AID403341, Type: Literature]
View
12
[SID103167732]
IC50 13.6Displacement of 8-anilino-1-naphthalene-sulfonic acid from human His-FABP4 expressed in Escherichia coli BL21 (DE3) cells after 3 mins [AID483947, Type: Literature]Fatty acid-binding protein, adipocyte [gi:119781]
View
13
[SID17388946]
Potency 17.7828qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
View
14
[SID103167732]
EC50 20.2Antiviral activity against HCV assessed as inhibition of HCV RNA replication in OR6 cells after 72 hrs by luciferase reporter assay [AID323922, Type: Literature]
View
15
[SID103167732]
IC50 27Inhibition of amidolytic activity of human recombinant soluble tissue factor/human factor 7a preincubated with factor 7a for 15 mins [AID402797, Type: Literature]
View
16
[SID17388946]
Potency 28.1838qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
17
[SID103167732]
IC50 30Inhibition of amidolytic activity of human recombinant soluble tissue factor/human factor 7a preincubated with factor 7a for 90 mins [AID402798, Type: Literature]
View
18
[SID144213397]
Ratio Potency (uM) 36.026qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
View
19
[SID103167732]
Km 39Activity of soybean lipoxygenase 1 [AID409935, Type: Literature]
View
20
[SID103167732]
IC50 41Inhibition of amidolytic activity of human tissue factor/human factor 7a [AID402795, Type: Literature]Tissue factor [gi:135666]
View