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Leukotriene A4 (CID 5280383) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Unspecified(9)
 
 
Top Targets:
MAPEG(3)
 
 
BioAssay Types:
Literature(6)
 
 
 
BioActivity Types:
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 12   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103265759]
IC50 2Inhibitory activity against 5-lipoxygenase [AID6952, Type: Literature]
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2
[SID103265759]
Km 7.6Kinetic parameter (Km) for hydrolysis of LTA4 hydrolase purified from human leukocytes [AID99753, Type: Literature]
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3
[SID103265759]
Km 7.6Michaelis-Menten constant of compound for Leukotriene A4 hydrolase catalyzed hydrolysis was determined [AID99754, Type: other]
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4
[SID103265759]
Kinetic parameter Vmax against LTA4 hydrolase purified from human leukocytes was determined [AID99755, Type: Literature]
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5
[SID103265759]
Maximum velocity of amino acid amides was tested as substrates for Leukotriene A4 hydrolase catalyzed hydrolysis [AID99758, Type: other]
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6
[SID103265759]
Kinetic parameter kcat against LTA4 hydrolase purified from human leukocytes [AID99759, Type: Literature]
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7
[SID103265759]
Ratio of catalytic constant to that of Michaelis-Menten constant for LTA4 hydrolase-catalyzed hydrolysis was determined [AID227954, Type: other]
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8
[SID103265759]
Ratio kcat /Km (1/M 1/s) [AID234198, Type: Literature]
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9
[SID103265759]
Substrates for human microsomal glutathione transferase LTC4S [AID589016, Type: other]Leukotriene C4 synthase [gi:2833283]
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10
[SID103265759]
Substrates for human microsomal glutathione transferase MGST2 [AID589018, Type: other]Microsomal glutathione S-transferase 2 [gi:2842764]
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11
[SID103265759]
Substrates for human microsomal glutathione transferase MGST3 [AID589019, Type: other]Microsomal glutathione S-transferase 3 [gi:7387731]
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12
[SID103265759]
Inhibitory activity against 5-lipoxygenase at a dose of 0.1 mM [AID6959, Type: Literature]
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