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Bilirubin (CID 5280352) - Compound BioActivity Data
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BioActivity Outcomes:
Active(12)
 
 
Inactive(54)
 
 
Inconclusive(19)
 
 
Unspecified(24)
 
 
Top Targets:
KAZAL SLC21(8)
 
 
GT1 Gtf like(7)
 
 
PLDc mTdp1 2(3)
 
 
 
globin(2)
 
 
NR LBD TR(2)
 
 
BioAssay Types:
Confirmatory(68)
 
 
 
 
Literature(27)
 
 
 
Screening(7)
 
 
 
BioActivity Types:
Potency(66)
 
 
 
 
Ki(2)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 104    Data Row: 109   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103619919]
Ki 0.72Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977601, Type: Literature]
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2
[SID103619919]
IC50 1.31826pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977600, Type: Literature]
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3
[SID103619919]
Ki 2.63Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977604, Type: Literature]
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4
[SID103619919]
IC50 3.38844pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977603, Type: Literature]
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5
[SID26749657]
Potency 10qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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6
[SID26749657]
Potency 25.1189qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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7
[SID26749657]
Potency 25.1189qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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8
[SID26749657]
Potency 39.8107qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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9
[SID10319019]
Compound Screen Assay, Human DHRS6 [AID510, Type: screening]unnamed protein product [Homo sapiens] [gi:14598968]
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10
[SID10319019]
Compound Screen Assay, Human HSD11B1 [AID398, Type: other]corticosteroid 11-beta-dehydrogenase isozyme 1 [Homo sapiens] [gi:5031765]
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11
[SID10319019]
Compound Screen Assay, Human PECR [AID392, Type: screening]peroxisomal trans-2-enoyl-CoA reductase [Homo sapiens] [gi:19923817]
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12
[SID10319019]
Compound Screen Assay, Human BLVRA [AID516, Type: screening]biliverdin reductase A precursor [Homo sapiens] [gi:33589854]
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13
[SID103619919]
Km 0.0076TP_TRANSPORTER: uptake in Xenopus laevis oocytes [AID680553, Type: Literature]Solute carrier organic anion transporter family member 1B1 [gi:12643959]
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14
[SID103619919]
Km 0.0391TP_TRANSPORTER: uptake in Xenopus laevis oocytes [AID680209, Type: Literature]Solute carrier organic anion transporter family member 1B3 [gi:27734563]
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15
[SID103619919]
TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 10 uM) by Bilirubin at a concentration of 100 u M in Xenopus laevis oocytes [AID680382, Type: Literature]Solute carrier organic anion transporter family member 1B3 [gi:27734563]
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16
[SID103619919]
Specific activity of expressed human recombinant UGT1A9 [AID624612, Type: Literature]UDP-glucuronosyltransferase 1-9 [gi:29839451]
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17
[SID103619919]
Specific activity of expressed human recombinant UGT1A6 [AID624609, Type: Literature]UDP-glucuronosyltransferase 1-6 [gi:29840832]
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18
[SID103619919]
Substrates of transporters of clinical importance in the absorption and disposition of drugs, OATP1B1 [AID588962, Type: Literature]Solute carrier organic anion transporter family member 1B1 [gi:12643959]
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19
[SID103619919]
TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 10 uM) by Bilirubin at a concentration of 100 u M in Xenopus laevis oocytes [AID680734, Type: Literature]Solute carrier organic anion transporter family member 1B1 [gi:12643959]
View
20
[SID103619919]
Km TP_TRANSPORTER: uptake in OATP-C-expressing HEK293 cells [AID681365, Type: Literature]Solute carrier organic anion transporter family member 1B1 [gi:12643959]
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