Bookmark and Share
carbamylhydrazine (CID 5196) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(134)
 
 
Inconclusive(15)
 
 
Unspecified(4)
 
 
Top Targets:
p450(9)
 
 
 
7TM GPCR Srx(6)
 
 
 
HSD10-like SD..(4)
 
 
Pyr redox dim(4)
 
 
PIKKc TOR(4)
 
 
BioAssay Types:
Confirmatory(133)
 
 
 
Literature(13)
 
 
 
 
BioActivity Types:
Potency(112)
 
 
 
IC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 143    Data Row: 159   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103236089]
IC50 0.0067Compound was evaluated for inhibition of Microbial tyramine oxidase [AID215956, Type: Literature]
View
2
[SID103236089]
IC50 6.7Inhibitory concentration for human liver monoamine oxidase A [AID241583, Type: Literature]Amine oxidase [flavin-containing] A [gi:113978]
View
3
[SID103236089]
IC50 6.7Inhibitory concentration for human liver monoamine oxidase B [AID241584, Type: Literature]Amine oxidase [flavin-containing] B [gi:113980]
View
4
[SID103236089]
Antinociceptive activity in Swiss mouse assessed inhibition of formaldehyde-induced paw licking at 0.31 mmol/kg, ip administered 30 mins prior to formaldehyde-challenge measured from 15 to 30 mins [AID649113, Type: Literature]
View
5
[SID103236089]
Antiinflammatory activity in Wistar rat assessed as inhibition of carrageenan-induced paw edema at 0.31 mmol/kg, ip administered 30 mins prior to carrageenan-challenge measured up to 6 hrs [AID649117, Type: Literature]
View
6
[SID103236089]
Antiinflammatory activity in Wistar rat assessed as inhibition of carrageenan-induced paw edema at 0.62 mmol/kg, ip administered 30 mins prior to carrageenan-challenge measured up to 6 hrs [AID649118, Type: Literature]
View
7
[SID103236089]
IC50 2192Activity against lymphocytic murine leukemia cell line L1210 using MTS/PES microculture tetrazolium assay [AID96456, Type: Literature]
View
8
[SID11111784]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
View
9
[SID103236089]
Calculated partition coefficient (clogP) [AID27913, Type: Literature]
View
10
[SID103236089]
Calculated partition coefficient (clogP) (SlogP) [AID28658, Type: Literature]
View
11
[SID90341010]
Potency 0.4467qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
View
12
[SID90341010]
Potency 4.7755qHTS screen for enhancers of Arylsulfatase A (ASA1): LOPAC Validation Assay [AID720538, Type: confirmatory]arylsulfatase A [Homo sapiens] [gi:220983390]
View
13
[SID90341010]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: HTRF assay [AID743207, Type: confirmatory]glucokinase regulatory protein [Homo sapiens] [gi:221625433]
View
14
[SID90341010]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: ADP-Glo assay [AID743206, Type: confirmatory]glucokinase regulatory protein [Homo sapiens] [gi:221625433]
View
15
[SID90341010]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: Diaphorase-coupled assay [AID743205, Type: confirmatory]glucokinase regulatory protein [Homo sapiens] [gi:221625433]
View
16
[SID90341010]
Potency Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
17
[SID90341010]
Potency qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
View
18
[SID90341010]
Potency qHTS for Inhibitors of Cell Surface uPA Generation: Validation Assay [AID493164, Type: confirmatory]plasminogen precursor [Mus musculus] [gi:257471003]
View
19
[SID11111784]
Potency qHTS Validation Assay for Activators of Leishmania Mexicana Pyruvate Kinase [AID959, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
View
20
[SID11111784]
Potency qHTS Validation Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase [AID945, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
View
21
[SID11111784]
Potency qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
View
22
[SID11111784]
Potency qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
23
[SID11111784]
Potency qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
24
[SID11111784]
Potency qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
25
[SID11111784]
Potency qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
26
[SID90341010]
Potency qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
View
27
[SID11111784]
Potency qHTS Assay for Inhibitors of 12-hLO (12-human lipoxygenase) [AID1452, Type: confirmatory]arachidonate 12-lipoxygenase, 12S-type [Homo sapiens] [gi:154426292]
View
28
[SID90341010]
Potency qHTS Validation Assay to Find Inhibitors of Phosphoglycerate Mutase [AID504548, Type: confirmatory]2,3-bisphosphoglycerate-independent phosphoglycerate mutase [Leishmania major strain Friedlin] [gi:157877932]
View
29
[SID11111784]
Potency qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Red Fluorophore) [AID892, Type: confirmatory]Chain A, Solution Structure Of The Brct-C Domain From Human Brca1 [gi:159162802]
View
30
[SID11111784]
Potency qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Green Fluorophore) [AID875, Type: confirmatory]Chain A, Solution Structure Of The Brct-C Domain From Human Brca1 [gi:159162802]
View
31
[SID90341010]
Potency Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation [AID504836, Type: Literature]heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [Homo sapiens] [gi:168984549]
View
32
[SID90341010]
Potency qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS [AID602332, Type: confirmatory]heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [Homo sapiens] [gi:168984549]
View
33
[SID90341010]
Potency qHTS for Inhibitors of ATXN expression: Validation [AID588378, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
View
34
[SID90341010]
Potency qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
View
35
[SID90341010]
Potency qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
View
36
[SID90341010]
Potency qHTS Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter [AID463106, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
View
37
[SID11111784]
Potency qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
View
38
[SID11111784]
Potency qHTS Assay for Anthrax Lethal Toxin Internalization [AID912, Type: confirmatory]lethal factor [Bacillus anthracis str. A2012] [gi:21392848]
View
39
[SID90341010]
Potency qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2 [AID488837, Type: confirmatory]eyes absent homolog 2 isoform a [Homo sapiens] [gi:26667227]
View
40
[SID90341010]
Potency qHTS Validation Assay for the Inhibitors of DNA Replication in Gram-Positive Bacteria [AID485295, Type: confirmatory]DNA polymerase III [Bacillus subtilis] [gi:30027657]
View
41
[SID11111784]
Potency qHTS Assay for Identification of Small Molecule Agonists for Hypoxia Response Element Signaling Pathway [AID914, Type: confirmatory]hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Homo sapiens] [gi:32879895]
View
42
[SID11111784]
Potency qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Homo sapiens] [gi:32879895]
View
43
[SID11111784]
Potency qHTS Assay for Inhibitors of Human Muscle Pyruvate Kinase [AID958, Type: confirmatory]pyruvate kinase PKM isoform b [Homo sapiens] [gi:33286420]
View
44
[SID11111784]
Potency qHTS Assay for Activators of Human Muscle Pyruvate Kinase [AID954, Type: confirmatory]pyruvate kinase PKM isoform b [Homo sapiens] [gi:33286420]
View
45
[SID11111784]
Potency qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Green Fluorophore) [AID879, Type: confirmatory]guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 [Homo sapiens] [gi:33946324]
View
46
[SID11111784]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6 [AID891, Type: confirmatory]cytochrome P450 2D6 isoform 1 [Homo sapiens] [gi:40805836]
View
47
[SID90341010]
Potency qHTS Validation Assay for Inhibitors for MPP8 Chromodomain Interactions with Methylated Histone Tails [AID488949, Type: confirmatory]M-phase phosphoprotein 8 [Homo sapiens] [gi:41055989]
View
48
[SID11111784]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors [AID901, Type: confirmatory]Inositol monophosphatase 1 [gi:44888968]
View
49
[SID90341010]
Potency High-Throughput Screening for Modulators of Cytosolic Chaperonin Activity: MmCpn Primary Screen [AID488978, Type: confirmatory]chaperonin GroEL [Methanococcus maripaludis S2] [gi:45359078]
View
50
[SID11111784]
Potency Counterscreen for Glucocerebrosidase Inhibitors: qHTS Assay for Rice alpha-Glucosidase at pH 5.0 [AID997, Type: confirmatory]putative alpha-glucosidase [Oryza sativa Japonica Group] [gi:52076901]
View