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carbamylhydrazine (CID 5196) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(136)
 
 
Inconclusive(15)
 
 
Unspecified(4)
 
 
Top Targets:
p450(9)
 
 
 
7TM GPCR Srx(6)
 
 
 
HSD10-like SD..(4)
 
 
Pyr redox dim(4)
 
 
PIKKc TOR(4)
 
 
BioAssay Types:
Confirmatory(134)
 
 
 
Literature(14)
 
 
 
 
BioActivity Types:
Potency(113)
 
 
 
IC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 145    Data Row: 161   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103236089]
IC50 0.0067Compound was evaluated for inhibition of Microbial tyramine oxidase [AID215956, Type: Literature]
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2
[SID103236089]
IC50 6.7Inhibitory concentration for human liver monoamine oxidase A [AID241583, Type: Literature]Amine oxidase [flavin-containing] A [gi:113978]
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3
[SID103236089]
IC50 6.7Inhibitory concentration for human liver monoamine oxidase B [AID241584, Type: Literature]Amine oxidase [flavin-containing] B [gi:113980]
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4
[SID103236089]
Antinociceptive activity in Swiss mouse assessed inhibition of formaldehyde-induced paw licking at 0.31 mmol/kg, ip administered 30 mins prior to formaldehyde-challenge measured from 15 to 30 mins [AID649113, Type: Literature]
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5
[SID103236089]
Antiinflammatory activity in Wistar rat assessed as inhibition of carrageenan-induced paw edema at 0.31 mmol/kg, ip administered 30 mins prior to carrageenan-challenge measured up to 6 hrs [AID649117, Type: Literature]
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6
[SID103236089]
Antiinflammatory activity in Wistar rat assessed as inhibition of carrageenan-induced paw edema at 0.62 mmol/kg, ip administered 30 mins prior to carrageenan-challenge measured up to 6 hrs [AID649118, Type: Literature]
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7
[SID103236089]
IC50 2192Activity against lymphocytic murine leukemia cell line L1210 using MTS/PES microculture tetrazolium assay [AID96456, Type: Literature]
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8
[SID11111784]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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9
[SID103236089]
Calculated partition coefficient (clogP) [AID27913, Type: Literature]
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10
[SID103236089]
Calculated partition coefficient (clogP) (SlogP) [AID28658, Type: Literature]
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11
[SID90341010]
Potency 0.4467qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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12
[SID90341010]
Potency 4.7755qHTS screen for enhancers of Arylsulfatase A (ASA1): LOPAC Validation Assay [AID720538, Type: confirmatory]arylsulfatase A [Homo sapiens] [gi:220983390]
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13
[SID90341010]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: Diaphorase-coupled assay [AID743205, Type: confirmatory]glucokinase regulatory protein [Homo sapiens] [gi:221625433]
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14
[SID90341010]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: ADP-Glo assay [AID743206, Type: confirmatory]glucokinase regulatory protein [Homo sapiens] [gi:221625433]
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15
[SID90341010]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: HTRF assay [AID743207, Type: confirmatory]glucokinase regulatory protein [Homo sapiens] [gi:221625433]
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16
[SID90341010]
Potency Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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17
[SID90341010]
Potency qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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18
[SID90341010]
Potency qHTS for Inhibitors of Cell Surface uPA Generation: Validation Assay [AID493164, Type: confirmatory]plasminogen precursor [Mus musculus] [gi:257471003]
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19
[SID11111784]
Potency qHTS Validation Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase [AID945, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
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20
[SID11111784]
Potency qHTS Validation Assay for Activators of Leishmania Mexicana Pyruvate Kinase [AID959, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
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