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Sodium Bicarbonate (CID 516892) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(4)
 
 
Unspecified(54)
 
 
Top Targets:
alpha CA I II..(15)
 
 
alpha CA IV X..(2)
 
 
alpha CA IX(2)
 
 
alpha CA V(1)
 
 
BioAssay Types:
Literature(54)
 
 
BioActivity Types:
Ki(36)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 58    Data Row: 58   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103446806]
Ki 100Inhibition of Leptonychotes weddellii alpha-carbonic anhydrase after 15 mins by CO2 hydrase assay at pH 7.5 [AID587132, Type: Literature]
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2
[SID103446806]
Ki 330Inhibition of Streptococcus pneumoniae beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID552785, Type: Literature]
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3
[SID103446806]
Ki 500Inhibition of Helicobacter pylori beta-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID730368, Type: Literature]
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4
[SID103446806]
Ki 640Inhibition of Salmonella Typhimurium carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598731, Type: Literature]
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5
[SID103446806]
Ki 660Inhibition of Flaveria bidentis beta-carbonic anhydrase-1 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730372, Type: Literature]
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6
[SID103446806]
Ki 750Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID730752, Type: Literature]
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7
[SID103446806]
Ki 750Inhibition of Helicobacter pylori alpha-carbonic anhydrase-catalyzed CO2 hydration reaction preincubated for 15 mins by stopped flow CO2 hydrase assay [AID677271, Type: Literature]
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8
[SID103446806]
Ki 5130Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID730751, Type: Literature]
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9
[SID103446806]
Ki 5800Inhibition of human recombinant CA8 mutant after 15 mins by stopped-flow CO2 hydration method [AID724720, Type: Literature]
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10
[SID103446806]
Ki 6600Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV [AID238543, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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11
[SID103446806]
Ki 6600Binding affinity against human cytosolic Carbonic anhydrase IV [AID238529, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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12
[SID103446806]
Ki 7000Inhibition of human recombinant CA11 mutant after 15 mins by stopped-flow CO2 hydration method [AID724718, Type: Literature]
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13
[SID103446806]
Ki 7200Inhibition of human recombinant CA10 mutant after 15 mins by stopped-flow CO2 hydration method [AID724719, Type: Literature]
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14
[SID103446806]
Ki 12000Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration method [AID724722, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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15
[SID103446806]
Ki 12000Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730754, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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16
[SID103446806]
Ki 12000Inhibition constant of anion against human carbonic anhydrase isozyme hCA I [AID238512, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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17
[SID103446806]
Ki 12000Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay [AID714401, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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18
[SID103446806]
Ki 12000Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598726, Type: Literature]Carbonic anhydrase 1 [gi:115449]
View
19
[SID103446806]
Ki 12000Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5 [AID587130, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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20
[SID103446806]
Ki 12000Binding affinity against human cytosolic Carbonic anhydrase I [AID238509, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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21
[SID103446806]
Ki 13000Binding affinity against human cytosolic Carbonic anhydrase IX [AID238530, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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22
[SID103446806]
Ki 13000Inhibition constant of anion against human carbonic anhydrase isozyme hCA IX [AID238545, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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23
[SID103446806]
Ki 15700Inhibition of Sulfurihydrogenibium azorense alpha-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID714403, Type: Literature]
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24
[SID103446806]
Ki 22800Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins measured for 10 to 100 secs by stopped flow CO2 hydration assay [AID647373, Type: Literature]
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25
[SID103446806]
Ki 27900Inhibition of Salmonella Typhimurium carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598732, Type: Literature]
View
26
[SID103446806]
Ki 33200Inhibition of Sulfurihydrogenibium yellowstonense YO3AOP1 alpha-carbonic anhydrase-catalyzed CO2 hydration reaction preincubated for 15 mins by stopped flow CO2 hydrase assay [AID677270, Type: Literature]
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27
[SID103446806]
Ki 82000Inhibition constant of anion against human carbonic anhydrase isozyme hCA V [AID238514, Type: Literature]
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28
[SID103446806]
Ki 82000Binding affinity against human cytosolic Carbonic anhydrase V [AID238510, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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29
[SID103446806]
Ki 85000Binding affinity against human cytosolic Carbonic anhydrase II [AID238528, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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30
[SID103446806]
Ki 85000Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5 [AID587131, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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31
[SID103446806]
Ki 85000Inhibition constant of anion against human carbonic anhydrase isozyme hCA II [AID238541, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
32
[SID103446806]
Ki 85000Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598728, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
33
[SID103446806]
Ki 85000Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay [AID714400, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
34
[SID103446806]
Ki 85000Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730373, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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35
[SID103446806]
Ki 85000Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration method [AID724721, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
36
[SID103446806]
Ki 85000Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730753, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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37
[SID103446806]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
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38
[SID103446806]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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39
[SID103446806]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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40
[SID103446806]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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41
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia [AID625279, Type: Literature]
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42
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis [AID625280, Type: Literature]
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43
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis [AID625281, Type: Literature]
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44
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis [AID625282, Type: Literature]
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45
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests [AID625283, Type: Literature]
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46
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure [AID625284, Type: Literature]
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47
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis [AID625285, Type: Literature]
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48
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis [AID625286, Type: Literature]
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49
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly [AID625287, Type: Literature]
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50
[SID103446806]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice [AID625288, Type: Literature]
View