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miglustat (CID 51634) - Compound BioActivity Data
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BioActivity Outcomes:
Active(56)
 
 
Inactive(109)
 
 
Inconclusive(6)
 
 
Unspecified(73)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
DUF608(6)
 
 
 
GH31 MGAM SI..(5)
 
 
 
BioAssay Types:
Literature(146)
 
 
 
 
Confirmatory(67)
 
 
 
Summary(24)
 
 
Screening(2)
 
 
BioActivity Types:
Potency(85)
 
 
 
IC50(53)
 
 
 
Ki(3)
 
 
 
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 244    Data Row: 244   Total Pages: 13   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103277564]
IC50 0.1Inhibition of lysosomal alpha-glucosidase by HPLC [AID466672, Type: Literature]
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2
[SID103277564]
IC50 0.1Inhibition of human lysosomal alpha glucosidase [AID437995, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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3
[SID103277564]
IC50 0.14Inhibition of conduritol beta-epoxide-sensitive mouse glucosylceramidase [AID386381, Type: Literature]Non-lysosomal glucosylceramidase [gi:143018443]
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4
[SID103277564]
IC50 0.23Inhibition of human GBA2 [AID437994, Type: Literature]Non-lysosomal glucosylceramidase [gi:143018392]
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5
[SID103277564]
IC50 0.23Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysis [AID652573, Type: Literature]Non-lysosomal glucosylceramidase [gi:143018392]
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6
[SID103277564]
IC50 0.23Inhibition of GBA2 by HPLC [AID466671, Type: Literature]
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7
[SID103277564]
IC50 0.23Inhibition of recombinant GBA2 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assay [AID553254, Type: Literature]
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8
[SID103277564]
IC50 0.3Inhibition of non-lysosomal glucosylceramidase [AID700852, Type: Literature]
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9
[SID103277564]
IC50 0.42Inhibitory activity against alpha-Glucosidase from rice [AID240826, Type: Literature]
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10
[SID103277564]
IC50 0.5Inhibition of sucrase by HPLC [AID466667, Type: Literature]
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11
[SID103277564]
IC50 0.58Inhibition of Sucrase in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method [AID208985, Type: Literature]
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12
[SID103277564]
IC50 0.6Inhibition of sucrase in mouse intestinal input by glucose release assay [AID553255, Type: Literature]Sucrase-isomaltase, intestinal [Cricetulus griseus] [gi:344247361]
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13
[SID103277564]
IC50 1Inhibition of rice alpha glucosidase [AID437996, Type: Literature]
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14
[SID103277564]
IC50 2.1Inhibition of Glycosidases (maltase) in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method maltase [AID104668, Type: Literature]
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15
[SID103277564]
IC50 2.1Inhibition of rat intestinal maltase using disaccharide [AID241705, Type: Literature]
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16
[SID103277564]
IC50 2.1Inhibition of rat intestinal maltase using moltose as substrate [AID711104, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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17
[SID103277564]
IC50 2.7Inhibition of rat intestinal isomaltase using isomaltase as substrate [AID711103, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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18
[SID103277564]
IC50 2.7Inhibition of rat intestinal isomaltase using disaccharide [AID241803, Type: Literature]
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19
[SID103277564]
IC50 2.7Inhibition of Glycosidases (isomaltase)in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method [AID91639, Type: Literature]
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20
[SID103277564]
Ki 3.7Competitive Inhibitory activity against Endoplasmic reticulum Alpha-Glucosidase II [AID36810, Type: Literature]
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