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MLS003235758 (CID 51361200) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(190)
 
 
Top Targets:
7TM GPCR Srsx(8)
 
 
 
7TM GPCR Srx(7)
 
 
RasGEF(4)
 
 
Peptidase C48(4)
 
 
 
NR DBD CAR(3)
 
 
BioAssay Types:
Screening(148)
 
 
 
Confirmatory(37)
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(34)
 
 
IC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 181    Data Row: 197   Total Pages: 10   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID121285879]
IC50 39.9Dose response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using Nedd8 Protein Substrate [AID624322, Type: confirmatory]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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2
[SID121285879]
qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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3
[SID121285879]
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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4
[SID121285879]
Epi Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of human tyrosyl-DNA phosphodiesterase 2 (TDP2) [AID720702, Type: screening]tyrosyl-DNA phosphodiesterase 2 [Homo sapiens] [gi:23510348]
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5
[SID121285879]
Epi Absorbance-based biochemical high throughput confirmation assay to identify inhibitors of human tyrosyl-DNA phosphodiesterase 2 (TDP2) [AID743263, Type: screening]tyrosyl-DNA phosphodiesterase 2 [Homo sapiens] [gi:23510348]
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6
[SID121285879]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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7
[SID121285879]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]integrase, partial [Human immunodeficiency virus 1] [gi:2853980]
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8
[SID121285879]
Potency 0.631qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen [AID720542, Type: confirmatory]apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] [gi:23496270]
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9
[SID121285879]
IC50 63.5Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate [AID651559, Type: confirmatory]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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10
[SID121285879]
IC50 128.345Epi Absorbance-based biochemical high throughput dose response assay to identify inhibitors of human tyrosyl-DNA phosphodiesterase 2 (TDP2) [AID743297, Type: confirmatory]tyrosyl-DNA phosphodiesterase 2 [Homo sapiens] [gi:23510348]
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11
[SID121285879]
uHTS identification of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay [AID588489, Type: screening]polyadenylate-binding protein 1 [Homo sapiens] [gi:46367787]
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12
[SID121285879]
Potency qHTS of Nrf2 Activators [AID624171, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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13
[SID121285879]
uHTS identification of small molecule modulators of myocardial damage [AID588492, Type: screening]
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14
[SID121285879]
Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588674, Type: screening]
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15
[SID121285879]
Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588692, Type: screening]
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16
[SID121285879]
Potency qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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17
[SID121285879]
uHTS determination of small molecule cytotoxicity in a fluorescence assay to identify cystic fibrosis induced NFkb Inhibitors [AID602141, Type: screening]
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18
[SID121285879]
Full deck counterscreen for positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602247, Type: screening]
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19
[SID121285879]
Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_SinglePoint_HTS_Activity [AID743287, Type: screening]
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20
[SID121285879]
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity [AID743397, Type: screening]
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