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BioActivity Data for Compound MLS003271268 (CID 51360281)

BioActivity Outcomes:
Active(5)
 
 
Inactive(188)
 
 
Inconclusive(1)
 
 
Top Targets:
7tm 4(15)
 
 
RasGEF(4)
 
 
Toxin trans(3)
 
 
NR DBD CAR(3)
 
 
FReD(2)
 
 
BioAssay Types:
Screening(146)
 
 
 
Confirmatory(36)
 
 
 
 
Literature(9)
 
 
BioAssay Categories:
Organism-base..(4)
 
 
Biochemical(45)
 
 
 
Toxicity(2)
 
 
Cell-based(58)
 
 
 
BioActivity Types:
Potency(34)
 
 
 
EC50(1)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 180    Data Row: 194   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID121284920]
IC50 3.974Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). [AID687013, Type: confirmatory]galanin receptor type 3 [Homo sapiens] [gi:4503907]
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2
[SID121284920]
Fluorescence polarization-based biochemical high throughput primary assay to identify inhibitors of sialic acid acetylesterase (SIAE) [AID1053197, Type: screening]Sialate O-acetylesterase [gi:74734243]
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3
[SID121284920]
Fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of sialic acid acetylesterase (SIAE) [AID1117263, Type: screening]Sialate O-acetylesterase [gi:74734243]
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4
[SID121284920]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID651719, Type: screening]galanin receptor type 3 [Homo sapiens] [gi:4503907]
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5
[SID121284920]
Fluorescence-based cell-based primary high throughput confirmation assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID652245, Type: screening]galanin receptor type 3 [Homo sapiens] [gi:4503907]
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6
[SID121284920]
Potency 15.8489qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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7
[SID121284920]
EC50 29.922Counterscreen for antagonists of the galanin Receptor 3 (GalR3): Fluorescence-based cell-based high throughput dose response assay to identify non specific activators of the parental HEK-CNG cells. [AID687015, Type: confirmatory]
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8
[SID121284920]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
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9
[SID121284920]
High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_SinglePoint_HTS_Activity_Set2 [AID743238, Type: screening]
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10
[SID121284920]
uHTS determination of small molecule cytotoxicity in a fluorescence assay to identify cystic fibrosis induced NFkb Inhibitors [AID602141, Type: screening]
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11
[SID121284920]
Full deck counterscreen for positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602247, Type: screening]
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12
[SID121284920]
Full deck counterscreen for agonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602248, Type: screening]
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13
[SID121284920]
Full deck counterscreen for antagonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective inhibitors and assay artifacts using the parental CHOK1 cell line [AID602250, Type: screening]
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14
[SID121284920]
Potency qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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15
[SID121284920]
uHTS luminescent assay for identification of compounds that enhance the survival of human induced pluripotent stem cells when cultured as single cells [AID602274, Type: screening]
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16
[SID121284920]
Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588692, Type: screening]
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17
[SID121284920]
Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588674, Type: screening]
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18
[SID121284920]
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening] [geneid:3205]
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19
[SID121284920]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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20
[SID121284920]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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