MLS001074624 (CID 51358932) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(29)
 
 
Inactive(405)
 
 
Inconclusive(13)
 
 
Unspecified(7)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
 
 
7TM GPCR Srsx(6)
 
 
BRLZ(5)
 
 
Peptidase C48(5)
 
 
Nuc rec co-ac..(4)
 
 
BioAssay Types:
Screening(323)
 
 
 
 
Confirmatory(116)
 
 
 
 
 
Literature(8)
 
 
BioActivity Types:
Potency(91)
 
 
 
 
IC50(19)
 
 
 
 
EC50(4)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 333    Data Row: 454   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID74373417]
IC50 2.54Dose response counterscreen for EBI2 assay utilizing the enzyme, b-galactosidase [AID652193, Type: confirmatory]Beta-galactosidase [gi:75404427]
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2
[SID74373417]
EC50 10.8Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr2 with Hit compounds from Cherry Pick1 [AID588604, Type: confirmatory]drug resistance protein 2 [Candida albicans] [gi:93115982]
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3
[SID74373417]
EC50 11.1Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr1 with Hit compounds from Cherry Pick1 [AID588606, Type: confirmatory]drug resistance protein 1 [Candida albicans] [gi:93115976]
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4
[SID74373417]
EC50 21.2Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1 [AID588608, Type: confirmatory]
View
5
[SID74373417]
 Single concentration confirmation of uHTS hits from a small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay [AID651997, Type: screening]
View
6
[SID74373417]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]
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7
[SID74373417]
 Single concentration validation of small molecule antagonists of the EBI2 receptor via a luminescent beta-galactosidase assay [AID652176, Type: screening]
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8
[SID74373417]
 Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
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9
[SID121282683]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]
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10
[SID74373417]
 Flow Cytometric HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Cherry Pick1 compound set [AID588518, Type: screening]
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11
[SID74373417]
 Flow Cytometric HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr1 with Cherry Pick1 compound set [AID588522, Type: screening]drug resistance protein 1 [Candida albicans] [gi:93115976]
View
12
[SID121282683]
 Single concentration validation of small molecule antagonists of the EBI2 receptor via a luminescent beta-galactosidase assay [AID652176, Type: screening]
View
13
[SID121282683]
 Single concentration confirmation of uHTS hits from a small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay [AID651997, Type: screening]
View
14
[SID74373417]
 uHTS identification of small molecule antagonists of the APJ receptor via a luminescent beta-arrestin assay [AID2521, Type: screening]APLNR gene product [Homo sapiens] [gi:4885057]
View
15
[SID74373417]
 uHTS identification of small molecule antagonists of the APJ receptor via a luminescent beta-arrestin assay [AID2521, Type: screening]APLNR gene product [Homo sapiens] [gi:4885057]
View
16
[SID74373417]
 uHTS identification of small molecule antagonists of the CCR6 receptor via a luminescent beta-arrestin assay [AID493098, Type: screening]CCR6 gene product [Homo sapiens] [gi:37187860]
View
17
[SID74373417]
 uHTS identification of small molecule antagonists of the CCR6 receptor via a luminescent beta-arrestin assay [AID493098, Type: screening]CCR6 gene product [Homo sapiens] [gi:37187860]
View
18
[SID74373417]
 uHTS identification of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID602261, Type: screening]FASN gene product [Homo sapiens] [gi:41872631]
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19
[SID74373417]
 uHTS identification of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID602261, Type: screening]FASN gene product [Homo sapiens] [gi:41872631]
View
20
[SID74373417]
 uHTS identification of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID602261, Type: screening]FASN gene product [Homo sapiens] [gi:41872631]
View
21
[SID74373417]
 uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay [AID651636, Type: screening]GPR183 gene product [Homo sapiens] [gi:4826706]
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22
[SID121282683]
 uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay [AID651636, Type: screening]GPR183 gene product [Homo sapiens] [gi:4826706]
View
23
[SID74373417]
 Single concentration confirmation of uHTS hits from a small molecule antagonists of the APJ receptor via a luminescent beta-arrestin assay [AID2766, Type: screening]APLNR gene product [Homo sapiens] [gi:4885057]
View
24
[SID74373417]
 Single concentration confirmation of uHTS hits from a small molecule antagonists of the APJ receptor via a luminescent beta-arrestin assay [AID2766, Type: screening]APLNR gene product [Homo sapiens] [gi:4885057]
View
25
[SID74373417]
 uHTS identification of inhibitors of NadD in a Colorimetric assay [AID602399, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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26
[SID121282683]
 uHTS identification of inhibitors of NadD in a Colorimetric assay [AID602399, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
View
27
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_5, Type: confirmatory]CCR6 gene product [Homo sapiens] [gi:37187860]
View
28
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_5, Type: confirmatory]CCR6 gene product [Homo sapiens] [gi:37187860]
View
29
[SID74373417]
 Counterscreen for inverse agonists of OPRM1-OPRD1 heterodimerization: luminescence-based cell-based full-deck high throughput screening assay to identify inverse agonists of 5-hydroxytryptamine (serotonin) 5A receptor (HTR5A) [AID504634, Type: screening]HTR5A gene product [Homo sapiens] [gi:13236497]
View
30
[SID74373417]
 Counterscreen for inverse agonists of OPRM1-OPRD1 heterodimerization: luminescence-based cell-based full-deck high throughput screening assay to identify inverse agonists of 5-hydroxytryptamine (serotonin) 5A receptor (HTR5A) [AID504634, Type: screening]HTR5A gene product [Homo sapiens] [gi:13236497]
View
31
[SID74373417]
 Counterscreen for inverse agonists of OPRM1-OPRD1 heterodimerization: luminescence-based cell-based full-deck high throughput screening assay to identify inverse agonists of 5-hydroxytryptamine (serotonin) 5A receptor (HTR5A) [AID504634, Type: screening]HTR5A gene product [Homo sapiens] [gi:13236497]
View
32
[SID74373417]
 Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504357, Type: screening]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
33
[SID74373417]
 Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504357, Type: screening]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
34
[SID74373417]
 Single concentration confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor via a luminescent beta-arrestin assay [AID602409, Type: screening]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
35
[SID74373417]
 Single concentration confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor via a luminescent beta-arrestin assay [AID602409, Type: screening]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
36
[SID74373417]
 uHTS identification of CXCR6 Inhibitors in a B-arrestin luminescence assay [AID602244, Type: screening]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
37
[SID74373417]
 uHTS identification of CXCR6 Inhibitors in a B-arrestin luminescence assay [AID602244, Type: screening]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
38
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_7, Type: confirmatory]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
39
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_7, Type: confirmatory]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
40
[SID121282683]
 uHTS identification of CXCR6 Inhibitors in a B-arrestin luminescence assay [AID602244, Type: screening]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
41
[SID121282683]
 uHTS identification of CXCR6 Inhibitors in a B-arrestin luminescence assay [AID602244, Type: screening]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
42
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_1, Type: confirmatory]APLNR gene product [Homo sapiens] [gi:4885057]
View
43
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_1, Type: confirmatory]APLNR gene product [Homo sapiens] [gi:4885057]
View
44
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_2, Type: confirmatory]APLNR gene product [Homo sapiens] [gi:4885057]
View
45
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_2, Type: confirmatory]APLNR gene product [Homo sapiens] [gi:4885057]
View
46
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_3, Type: confirmatory]APLNR gene product [Homo sapiens] [gi:4885057]
View
47
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_3, Type: confirmatory]APLNR gene product [Homo sapiens] [gi:4885057]
View
48
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_8, Type: confirmatory]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
49
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_8, Type: confirmatory]CXCR6 gene product [Homo sapiens] [gi:5730106]
View
50
[SID74373417]
IC50 Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_9, Type: confirmatory]CXCR6 gene product [Homo sapiens] [gi:5730106]
View