KUC109070N (CID 51035287) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(5)
 
 
BioAssay Types:
Confirmatory(6)
 
 
 
BioActivity Types:
IC50(4)
 
 
EC50(2)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID117695373]
EC50 2.02SAR analysis of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID540312, Type: confirmatory]
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2
[SID117695373]
IC50 27.9SAR analysis of cytotoxicity in CHO-XBP1 cells after 24 hours of exposure to small molecule activators of the apoptotic arm of the Unfolded Protein response [AID588558, Type: confirmatory]
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3
[SID117695373]
IC50 45.9SAR analysis of cytotoxicity in CHO-CHOP cells after 24 hours of exposure to small molecule activators of the apoptotic arm of the Unfolded Protein Response [AID588556, Type: confirmatory]
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4
[SID117695373]
IC50 80SAR analysis of cytotoxicity in the CHO-CHOP cells after 6 hours of exposure to small molecule activators of the apoptotic arm of the Unfolded Protein response [AID588557, Type: confirmatory]
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5
[SID117695373]
IC50 80SAR analysis of cytotoxicity in CHO-XBP1 cells following 6 hours of exposure to small molecule activators of the apoptotic arm of the Unfolded Protein response [AID588570, Type: confirmatory]
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6
[SID117695373]
EC50 80SAR analysis counterscreen of small molecule activators of the apoptotic arm of the Unfolded Protein Response via a luminescent-based reporter assay [AID540305, Type: confirmatory]
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