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2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (CID 50985951) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Top Targets:
KCNQ channel(3)
 
 
BioAssay Types:
Confirmatory(2)
 
 
BioActivity Types:
IC50(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3    Data Row: 3   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID116933760]
IC50 0.08SAR analysis for compounds that inhibit KCNQ2 potassium channels on automated electrophysiological assay, CRC2 [AID588426, Type: confirmatory]potassium voltage-gated channel subfamily KQT member 2 [Rattus norvegicus] [gi:18959272]
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2
[SID116933760]
IC50 2.92Dose response assay of SAR compounds for the identification of selective inhibitors of KCNQ2 potassium channels in the KCNQ1 expressing cells on automated patch clamp [AID588425, Type: confirmatory]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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3
[SID116933760]
SAR-Confirmatory assay to confirm a potent KCNQ2 inhibitor using manual electrophysiology [AID588635, Type: other]potassium voltage-gated channel subfamily KQT member 2 [Rattus norvegicus] [gi:18959272]
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