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CHEMBL2163350 (CID 50898276) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Top Targets:
KCNQ channel(2)
 
 
BioAssay Types:
Confirmatory(2)
 
 
Literature(1)
 
 
BioActivity Types:
IC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3    Data Row: 3   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID163327459]
IC50 5.27Antagonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay [AID697785, Type: Literature]
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2
[SID110167740]
IC50 5.27SAR analysis for compounds that inhibit KCNQ2 potassium channels on automated electrophysiological assay, CRC2 [AID588426, Type: confirmatory]potassium voltage-gated channel subfamily KQT member 2 [Rattus norvegicus] [gi:18959272]
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3
[SID110167740]
IC50 13.65Dose response assay of SAR compounds for the identification of selective inhibitors of KCNQ2 potassium channels in the KCNQ1 expressing cells on automated patch clamp [AID588425, Type: confirmatory]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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