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MLS003659050 (CID 50897759) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(22)
 
 
Unspecified(3)
 
 
Top Targets:
NR DBD CAR(3)
 
 
FReD(2)
 
 
ZnMc TACE lik..(2)
 
 
AdoMet MTases(1)
 
 
PI-PLCc gamma(1)
 
 
BioAssay Types:
Screening(21)
 
 
Confirmatory(8)
 
 
 
Literature(5)
 
 
 
BioActivity Types:
IC50(4)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 35    Data Row: 36   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID109967235]
IC50 3.51A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (6) [AID504526, Type: confirmatory]
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2
[SID163331461]
EC50 4.2Antiviral activity against Respiratory syncytial virus Long infected in human Hep2 cells assessed as reduction in virus-induced cytopathogenicity by Cell Titer-Glo assay [AID701507, Type: Literature]
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3
[SID109967235]
IC50 4.6A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (10) [AID504827, Type: confirmatory]
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4
[SID109967235]
Average IC50 4.8A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (8) [AID504820, Type: confirmatory]
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5
[SID109967235]
IC50 9.33A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (7) [AID504655, Type: confirmatory]
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6
[SID163331461]
CC50 44.2Cytotoxicity against human Hep2 cells by Cell Titer-Glo assay [AID701508, Type: Literature]
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7
[SID109967235]
Average CC50 46.35An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (8) [AID504818, Type: confirmatory]
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8
[SID109967235]
CC50 47.7An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (10) [AID504825, Type: confirmatory]
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9
[SID109967235]
CC50 50An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (6) [AID504509, Type: confirmatory]
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10
[SID109967235]
A Time of Addition Assay to evaluate New Inhibitors of Respiratory syncytial virus (RSV) [AID504829, Type: other]
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11
[SID109967235]
A Plaque Reduction Assay to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) [AID504830, Type: other]
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12
[SID163331461]
Selectivity index, ratio of CC50 for human Hep2 cells to EC50 for Respiratory syncytial virus Long infected in human Hep2 cells [AID701509, Type: Literature]
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13
[SID163331461]
Antiviral activity against Respiratory syncytial virus Long infected in human Hep2 cells assessed as log reduction in virus titer at 25 uM by virus plaque reduction assay [AID701510, Type: Literature]
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14
[SID163331461]
Cytotoxicity against uninfected human Hep2 cells assessed as cell viability at 25 uM measured after 144 hrs by Cell Titer-Glo assay [AID701513, Type: Literature]
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15
[SID109967235]
CC50 50An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (7) [AID504674, Type: confirmatory]
View
16
[SID143472249]
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM10. [AID720582, Type: screening]ADAM10 [Homo sapiens] [gi:2393947]
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17
[SID143472249]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]integrase, partial [Human immunodeficiency virus 1] [gi:2853980]
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18
[SID143472249]
TRFRET-based cell-based primary high throughput screening assay to identify inhibitors of cell surface Prion Protein (PRPC) [AID720596, Type: screening]major prion protein preproprotein [Homo sapiens] [gi:4506113]
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19
[SID143472249]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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20
[SID143472249]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2) [AID686940, Type: screening]COUP transcription factor 2 isoform a [Homo sapiens] [gi:14149746]
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