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AC1NO0T3 (CID 5080386) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(5)
 
 
Top Targets:
G6PD N(3)
 
 
14-3-3 gamma(1)
 
 
G6PD C(1)
 
 
BioAssay Types:
Confirmatory(4)
 
 
Screening(1)
 
 
BioActivity Types:
IC50(4)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124756845]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay [AID588415, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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2
[SID124756845]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal assay utilizing the direct end-point detection of NADPH [AID588588, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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3
[SID124756845]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal kinetic assay utilizing the direct detection of NADPH [AID588593, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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4
[SID124756845]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase using a Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay [AID588414, Type: confirmatory]glucose-6-phosphate 1-dehydrogenase isoform b [Homo sapiens] [gi:108773793]
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5
[SID24359212]
HTS for 14-3-3 protein interaction modulators [AID422, Type: screening]14-3-3 protein gamma [Homo sapiens] [gi:21464101]
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