Bookmark and Share
Risperidone (CID 5073) - Compound BioActivity Data
.
Filters: All Data » Active      
Filter selected
BioActivity Outcomes:
Active(245)
 
 
Top Targets:
7TM GPCR Srsx(52)
 
 
7TM GPCR Srx(40)
 
 
CAP ED(11)
 
 
FAM101(2)
 
 
DUF3353(1)
 
 
BioAssay Types:
Literature(192)
 
 
Confirmatory(40)
 
 
Screening(3)
 
 
BioActivity Types:
Ki(121)
 
 
IC50(57)
 
 
Potency(21)
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 210    Data Row: 245   Total Pages: 13   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103170825]
Ki 0.00014Ability to displace [3H]ketanserin from serotonergic 5-hydroxytryptamine 2 receptor [AID5258, Type: confirmatory]
View
2
[SID103170825]
Ki 0.00015Displacement of [3H]ketanserin from 5HT2A receptor in CRL:CD(SD)BR-COBS rat cortex by scintillation spectrometry [AID410335, Type: Literature]5-hydroxytryptamine receptor 2A [gi:112808]
View
3
[SID103170825]
Ki 0.00016Ability to inhibit the binding of iodine-125-labelled lysergic acid diethylamide([125I]-LSD) to the S-2A serotonin receptor. [AID5504, Type: Literature]
View
4
[SID103170825]
Ki 0.00016Binding affinity towards human serotonin 5-hydroxytryptamine 2A receptor [AID5197, Type: Literature]
View
5
[SID103170825]
Ki 0.00018Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 15 mins by liquid scintillation counting analysis [AID750651, Type: Literature]5-hydroxytryptamine receptor 2A [gi:112808]
View
6
[SID103170825]
Ki 0.0002The binding affinity was measured on 5-hydroxytryptamine 2 receptor in rat brain tissue [AID5303, Type: Literature]
View
7
[SID103170825]
Ki 0.0002Affinity for 5-hydroxytryptamine 2 receptor [AID5246, Type: Literature]5-hydroxytryptamine receptor 2A [gi:112808]
View
8
[SID103170825]
Ki 0.0002Affinity for 5-hydroxytryptamine 2 receptor [AID5246, Type: Literature]5-hydroxytryptamine receptor 2C [gi:112817]
View
9
[SID103170825]
Ki 0.0002Affinity for 5-hydroxytryptamine 2 receptor [AID5246, Type: Literature]5-hydroxytryptamine receptor 2B [gi:398970]
View
10
[SID103170825]
Ki 0.00025Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat brain cortex homogenate after 30 mins by liquid scintillation counting [AID1071729, Type: Literature]5-hydroxytryptamine receptor 2A [gi:112808]
View
11
[SID103170825]
Ki 0.00029Binding affinity to human cloned 5HT2A receptor [AID342784, Type: Literature]5-hydroxytryptamine receptor 2A [gi:543727]
View
12
[SID103170825]
Ki 0.00032The compound was measured at a dose 10 times the ED50 value for CAR block for production of catalepsy in the rat [AID184416, Type: Literature]
View
13
[SID103170825]
IC50 0.000346DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) [AID625192, Type: confirmatory]5-hydroxytryptamine receptor 2A [gi:543727]
View
14
[SID103170825]
Ki 0.00039Binding affinity for human 5-hydroxytryptamine 2A receptor [AID5199, Type: Literature]5-hydroxytryptamine receptor 2A [gi:543727]
View
15
[SID103170825]
Ki 0.00044Binding affinity towards human D2 dopamine receptor. [AID63070, Type: Literature]
View
16
[SID103170825]
Ki 0.000501Displacement of [3H]ketanserin from human cloned 5HT2A receptor [AID439066, Type: Literature]5-hydroxytryptamine receptor 2A [gi:543727]
View
17
[SID103170825]
Ki 0.000501Displacement of [3H]ketanserin from human 5-HT2A receptor [AID1062949, Type: Literature]5-hydroxytryptamine receptor 2A [gi:543727]
View
18
[SID103170825]
Ki 0.00054Relative binding affinity for D2 receptor and 5-hydroxytryptamine 2A receptor, ratio of Ki [AID5573, Type: Literature]D(2) dopamine receptor [gi:47117674]
View
19
[SID103170825]
Ki 0.00054Relative binding affinity for D2 receptor and 5-hydroxytryptamine 2A receptor, ratio of Ki [AID5573, Type: Literature]5-hydroxytryptamine receptor 2A [gi:112808]
View
20
[SID103170825]
Ki 0.00069Binding affinity towards human alpha-1 adrenergic receptor [AID36116, Type: Literature]
View