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N-{4-[1-(ethylsulfonyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenyl}methanesulfonamide (CID 5019487) - Compound BioActivity Data
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BioActivity Outcomes:
Active(10)
 
 
Inactive(682)
 
 
Inconclusive(19)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(20)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
Tryp SPc(8)
 
 
 
BioAssay Types:
Screening(481)
 
 
 
 
Confirmatory(206)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(151)
 
 
 
 
IC50(41)
 
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 646    Data Row: 712   Total Pages: 36   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17514390]
IC50 0.37007Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID652135, Type: confirmatory]fructose-bisphosphate aldolase [Mycobacterium tuberculosis H37Rv] [gi:15607504]
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2
[SID17514390]
IC50 0.98Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Fluorescence-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) dose response assay to identify assay artifacts [AID652145, Type: confirmatory]
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3
[SID17514390]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID588726, Type: screening]fructose-bisphosphate aldolase [Mycobacterium tuberculosis H37Rv] [gi:15607504]
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4
[SID17514390]
uHTS identification of inhibitors of Rpn11 in a Fluorescent Polarization assay [AID588493, Type: screening]PSMD14 protein [Homo sapiens] [gi:16306916]
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5
[SID17514390]
Single concentration confirmation of uHTS inhibitor hits from RPN11 in a Fluorescence Polarization assay [AID602318, Type: screening]PSMD14 protein [Homo sapiens] [gi:16306916]
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6
[SID17514390]
Activator for delta FosB/delta FosB homodimer Measured in Biochemical System Using Plate Reader - 2072-01_Activator_SinglePoint_HTS_Activity [AID493131, Type: screening]protein fosB [Mus musculus] [gi:6679827]
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7
[SID17514390]
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening] [geneid:3205]
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8
[SID17514390]
Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1529, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
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9
[SID17514390]
uHTS identification of small molecule inhibitors of Csn-mediated Deneddylation of Cullin-Ring Ligases, vis a fluorescence polarization assay [AID651999, Type: screening]COP9 signalosome complex subunit 5 [Homo sapiens] [gi:38027923]
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10
[SID17514390]
Single concentration validation of uHTS RPN11 inhibitor hits using a Thrombin Fluorescence Polarization assay [AID602333, Type: screening]TPA: prothrombin [Bos taurus] [gi:296479639]
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11
[SID17514390]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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12
[SID17514390]
Potency 35.4813qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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13
[SID17514390]
Potency 56.2341qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588456, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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14
[SID17514390]
IC50 Chemical Antagonists IAP-family anti-apoptotic proteins [AID1018, Type: confirmatory]X-linked inhibitor of apoptosis [Homo sapiens] [gi:8744934]
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15
[SID17514390]
Identification of VIF Inhibitors Measured in Cell-Based System Using Imaging - 2108-01_Inhibitor_SinglePoint_HTS_Activity [AID602346, Type: screening]Vif [Human immunodeficiency virus 1] [gi:9629361]
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16
[SID17514390]
TRFRET-based biochemical primary high throughput screening assay to identify small molecules that bind to the HIV-1-gp120 binding antibody, PG9 [AID624416, Type: screening]Envelope surface glycoprotein gp160, precursor [Human immunodeficiency virus 1] [gi:9629363]
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17
[SID17514390]
High Throughput Screen to Identify Compounds that Inhibit Class II HMG-CoA Reductases - Primary Screen [AID1066, Type: screening]acetyl-CoA acetyltransferase/HMG-CoA reductase [Enterococcus faecalis] [gi:9937384]
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18
[SID17514390]
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set [AID602162, Type: screening]ATP-binding cassette sub-family B member 6, mitochondrial [Homo sapiens] [gi:9955963]
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19
[SID17514390]
Fluorescence Polarization with Cer CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-01_Inhibitor_SinglePoint_HTS_Activity [AID504414, Type: screening]Golgi-associated PDZ and coiled-coil motif-containing protein isoform a [Homo sapiens] [gi:9966877]
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20
[SID17514390]
qHTS for Agonists of the Human Mucolipin Transient Receptor Potential 1 (TRPML1) [AID624414, Type: screening]mucolipin-1 [Homo sapiens] [gi:10092597]
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