AC1NLP3N (CID 4986791) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Inactive(73)
 
 
Inconclusive(9)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(6)
 
 
 
P53(4)
 
 
SAM PNT-ERG(3)
 
 
 
Pyr redox dim(3)
 
 
 
7TM GPCR Srw(2)
 
 
BioAssay Types:
Confirmatory(67)
 
 
 
Screening(15)
 
 
 
Literature(1)
 
 
BioActivity Types:
Potency(66)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 81    Data Row: 83   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24275618]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
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2
[SID24275618]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
View
3
[SID24275618]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
View
4
[SID24275618]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
View
5
[SID24275618]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
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6
[SID24275618]
Potency 0.631qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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7
[SID24275618]
Potency 0.631qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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8
[SID24275618]
Potency 0.7079qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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9
[SID24275618]
Potency 0.7079qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent) [AID485294, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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10
[SID24275618]
Potency 100HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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11
[SID24275618]
 qHTS for Agonists of the Human Mucolipin Transient Receptor Potential 1 (TRPML1) [AID624414, Type: screening]MCOLN1 gene product [Homo sapiens] [gi:10092597]
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12
[SID24275618]
 qHTS for Inhibitors of the Human Mucolipin Transient Receptor Potential 1 (TRPML1) [AID624415, Type: screening]MCOLN1 gene product [Homo sapiens] [gi:10092597]
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13
[SID24275618]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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14
[SID24275618]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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15
[SID24275618]
Potency qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588456, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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16
[SID24275618]
Potency qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588456, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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17
[SID24275618]
Potency qHTS Assay for Agonists of the Relaxin Receptor RXFP1 [AID2676, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
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18
[SID24275618]
Potency qHTS Assay for Agonists of the Relaxin Receptor RXFP1 [AID2676, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
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19
[SID24275618]
Potency qHTS for Inhibitors of Vif-A3G Interactions: qHTS [AID602310, Type: confirmatory]APOBEC3G gene product [Homo sapiens] [gi:13399304]
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20
[SID24275618]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors [AID901, Type: confirmatory]Inositol monophosphatase [gi:44888968]
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21
[SID24275618]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors [AID901, Type: confirmatory]Inositol monophosphatase [gi:44888968]
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22
[SID24275618]
Potency qHTS for Inhibitors of Vif-A3F Interactions: qHTS [AID602313, Type: confirmatory]APOBEC3F gene product [Homo sapiens] [gi:22907044]
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23
[SID24275618]
Potency qHTS Assay to Find Inhibitors of Phosphoglycerate Kinase [AID602233, Type: confirmatory]phosphoglycerate kinase [Trypanosoma brucei] [gi:115503961]
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24
[SID24275618]
Potency qHTS of TDP-43 Inhibitors [AID652104, Type: confirmatory]TAR DNA-binding protein 43 [gi:20140568]
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25
[SID24275618]
Potency qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
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26
[SID24275618]
Potency qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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27
[SID24275618]
Potency qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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28
[SID24275618]
Potency Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
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29
[SID24275618]
Potency qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
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30
[SID24275618]
Potency qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21 [AID2289, Type: confirmatory]
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31
[SID24275618]
Potency Nrf2 qHTS screen for inhibitors: counterscreen for cytotoxicity [AID504648, Type: confirmatory]
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32
[SID24275618]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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33
[SID24275618]
Potency qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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34
[SID24275618]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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35
[SID96111533]
 A screen for compounds that inhibit cell wall-associated teichoic acid synthesis in Staphylococcus aureus [AID463173, Type: screening]
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36
[SID96111533]
 A screen for compounds that inhibit cell wall-associated teichoic acid synthesis in Staphylococcus aureus [AID463173_1, Type: screening]
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37
[SID96111533]
 A screen for compounds that inhibit cell wall-associated teichoic acid synthesis in Staphylococcus aureus [AID463173_2, Type: screening]
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38
[SID24275618]
Potency qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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39
[SID24275618]
Potency qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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40
[SID24275618]
Potency Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon [AID493208, Type: confirmatory]MTOR gene product [Homo sapiens] [gi:4826730]
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41
[SID24275618]
Potency Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon [AID493208, Type: confirmatory]MTOR gene product [Homo sapiens] [gi:4826730]
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42
[SID24275618]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen [AID2100, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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43
[SID24275618]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen [AID2100, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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44
[SID24275618]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen [AID2100, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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45
[SID24275618]
Potency qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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46
[SID24275618]
Potency qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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47
[SID24275618]
Potency qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
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48
[SID24275618]
Potency qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
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49
[SID24275618]
Potency qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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50
[SID24275618]
Potency qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): qHTS [AID602179, Type: confirmatory]isocitrate dehydrogenase 1 [Homo sapiens] [gi:89573979]
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