Bookmark and Share

BioActivity Data for Compound MLS003659049 (CID 49842897)

BioActivity Outcomes:
Probe(1)
 
 
Active(15)
 
 
Inactive(23)
 
 
Unspecified(7)
 
 
Top Targets:
NR DBD CAR(3)
 
 
FReD(2)
 
 
ZnMc TACE lik..(2)
 
 
AdoMet MTases(1)
 
 
Esterase lipa..(1)
 
 
BioAssay Types:
Screening(23)
 
 
Confirmatory(12)
 
 
Literature(9)
 
 
 
BioAssay Categories:
Biochemical(17)
 
 
Toxicity(8)
 
 
 
ADME(2)
 
 
 
Cell-based(15)
 
 
 
 
BioActivity Types:
IC50(6)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 41    Data Row: 46   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104169543]
A Time of Addition Assay to evaluate New Inhibitors of Respiratory syncytial virus (RSV) [AID504829, Type: other]
View
2
[SID104169543]
IC50 Rep 1 1.5A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (11) [AID540264, Type: confirmatory]
View
3
[SID123058985]
Average IC50 1.7A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (8) [AID504820, Type: confirmatory]
View
4
[SID123058985]
IC50 Rep 1 1.7A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (11) [AID540264, Type: confirmatory]
View
5
[SID163338338]
EC50 2.3Antiviral activity against Respiratory syncytial virus Long infected in human Hep2 cells assessed as reduction in virus-induced cytopathogenicity by Cell Titer-Glo assay [AID701507, Type: Literature]
View
6
[SID104169543]
Average IC50 2.9A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (8) [AID504820, Type: confirmatory]
View
7
[SID104169543]
IC50 3.2A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (9) [AID504823, Type: confirmatory]
View
8
[SID104169543]
IC50 5.1A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (6) [AID504526, Type: confirmatory]
View
9
[SID104169543]
CC50 25.02An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (9) [AID504826, Type: confirmatory]
View
10
[SID163338338]
CC50 30.9Cytotoxicity against human Hep2 cells by Cell Titer-Glo assay [AID701508, Type: Literature]
View
11
[SID123058985]
CC50 Rep 1 32.9An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (11) [AID540266, Type: confirmatory]
View
12
[SID123058985]
Average CC50 32.9An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (8) [AID504818, Type: confirmatory]
View
13
[SID104169543]
CC50 Rep 1 34.7An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (11) [AID540266, Type: confirmatory]
View
14
[SID104169543]
Average CC50 36.2An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (8) [AID504818, Type: confirmatory]
View
15
[SID104169543]
CC50 50.4An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (6) [AID504509, Type: confirmatory]
View
16
[SID104169543]
A Plaque Reduction Assay to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) [AID504830, Type: other]
View
17
[SID163338338]
Selectivity index, ratio of CC50 for human Hep2 cells to EC50 for Respiratory syncytial virus Long infected in human Hep2 cells [AID701509, Type: Literature]
View
18
[SID163338338]
Cytotoxicity against uninfected human Hep2 cells assessed as cell viability at 25 uM measured after 144 hrs by Cell Titer-Glo assay [AID701513, Type: Literature]
View
19
[SID163338338]
Antiviral activity against Respiratory syncytial virus Long infected in human Hep2 cells assessed as post infection time duration of protection against virus-induced cytopathogenicity by Cell Titer-Glo assay [AID701514, Type: Literature]
View
20
[SID163338338]
Antiviral activity against Respiratory syncytial virus Long infected in human Hep2 cells assessed as protection against virus-induced cytopathogenicity by measuring cell viability at 24 hrs post infection by Cell Titer-Glo assay [AID701515, Type: Literature]
View