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MLS003659049 (CID 49842897) - Compound BioActivity Data
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BioActivity Outcomes:
Probe(1)
 
 
Active(15)
 
 
Inactive(21)
 
 
Unspecified(7)
 
 
Top Targets:
NR DBD CAR(3)
 
 
FReD(2)
 
 
ZnMc TACE lik..(2)
 
 
AdoMet MTases(1)
 
 
PI-PLCc gamma(1)
 
 
BioAssay Types:
Screening(21)
 
 
Confirmatory(12)
 
 
Literature(9)
 
 
 
BioActivity Types:
IC50(6)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 39    Data Row: 44   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104169543]
A Time of Addition Assay to evaluate New Inhibitors of Respiratory syncytial virus (RSV) [AID504829, Type: other]
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2
[SID104169543]
IC50 Rep 1 1.5A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (11) [AID540264, Type: confirmatory]
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3
[SID123058985]
Average IC50 1.7A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (8) [AID504820, Type: confirmatory]
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4
[SID123058985]
IC50 Rep 1 1.7A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (11) [AID540264, Type: confirmatory]
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5
[SID163338338]
EC50 2.3Antiviral activity against Respiratory syncytial virus Long infected in human Hep2 cells assessed as reduction in virus-induced cytopathogenicity by Cell Titer-Glo assay [AID701507, Type: Literature]
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6
[SID104169543]
Average IC50 2.9A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (8) [AID504820, Type: confirmatory]
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7
[SID104169543]
IC50 3.2A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (9) [AID504823, Type: confirmatory]
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8
[SID104169543]
IC50 5.1A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (6) [AID504526, Type: confirmatory]
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9
[SID104169543]
CC50 25.02An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (9) [AID504826, Type: confirmatory]
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10
[SID163338338]
CC50 30.9Cytotoxicity against human Hep2 cells by Cell Titer-Glo assay [AID701508, Type: Literature]
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11
[SID123058985]
CC50 Rep 1 32.9An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (11) [AID540266, Type: confirmatory]
View
12
[SID123058985]
Average CC50 32.9An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (8) [AID504818, Type: confirmatory]
View
13
[SID104169543]
CC50 Rep 1 34.7An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (11) [AID540266, Type: confirmatory]
View
14
[SID104169543]
Average CC50 36.2An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (8) [AID504818, Type: confirmatory]
View
15
[SID104169543]
CC50 50.4An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (6) [AID504509, Type: confirmatory]
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16
[SID104169543]
A Plaque Reduction Assay to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) [AID504830, Type: other]
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17
[SID163338338]
Selectivity index, ratio of CC50 for human Hep2 cells to EC50 for Respiratory syncytial virus Long infected in human Hep2 cells [AID701509, Type: Literature]
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18
[SID163338338]
Antiviral activity against Respiratory syncytial virus Long infected in human Hep2 cells assessed as log reduction in virus titer at 25 uM by virus plaque reduction assay [AID701510, Type: Literature]
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19
[SID163338338]
Aqueous solubility in PBS buffer [AID701511, Type: Literature]
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20
[SID163338338]
Chemical stability in 50% PBS/50% acetonitrile solution assessed as unchanged parent compound remaining after 48 hrs [AID701512, Type: Literature]
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