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BioActivity Data for Compound MLS003119869 (CID 49795478)

BioActivity Outcomes:
Active(4)
 
 
Inactive(191)
 
 
Inconclusive(4)
 
 
Top Targets:
7tm 4(17)
 
 
RasGEF(4)
 
 
SRC-1(3)
 
 
Toxin trans(3)
 
 
NR DBD CAR(3)
 
 
BioAssay Types:
Screening(151)
 
 
 
 
Confirmatory(35)
 
 
 
Literature(9)
 
 
BioAssay Categories:
Organism-base..(4)
 
 
Biochemical(48)
 
 
Toxicity(2)
 
 
Cell-based(56)
 
 
 
BioActivity Types:
Potency(35)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 185    Data Row: 199   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103163101]
uHTS identification of small molecule inhibitors of the mitochondrial permeability transition pore via an absorbance assay [AID602449, Type: screening]
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2
[SID103163101]
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening] [geneid:3205]
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3
[SID103163101]
Single concentration confirmation of uHTS inhibitor hits of the mitochondrial permeability transition pore via a fluorescent based assay [AID624504, Type: screening]
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4
[SID103163101]
Counterscreen for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1): Luminescence-based cell-based high throughput assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16). [AID588824, Type: screening]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
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5
[SID103163101]
Potency 35.4813qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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6
[SID103163101]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening] [geneid:2395]
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7
[SID103163101]
HTS to identify compounds that promote myeloid differentiation with Cherry Pick01 [AID651706, Type: screening] [geneid:3205]
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8
[SID103163101]
Full deck counterscreen for positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602247, Type: screening]
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9
[SID103163101]
Full deck counterscreen for agonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602248, Type: screening]
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10
[SID103163101]
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set [AID602162, Type: screening]ATP-binding cassette sub-family B member 6, mitochondrial [Homo sapiens] [gi:9955963]
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11
[SID103163101]
qHTS for Agonists of the Human Mucolipin Transient Receptor Potential 1 (TRPML1) [AID624414, Type: screening]mucolipin-1 [Homo sapiens] [gi:10092597]
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12
[SID103163101]
Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis & Epilepsy Measured in Biochemical System Using RT-PCR - 7012-01_Inhibitor_SinglePoint_HTS_Activity [AID651658, Type: screening]fibroblast growth factor 22 isoform 1 precursor [Homo sapiens] [gi:10190672]
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13
[SID103163101]
Luminescence-based cell-based high throughput primary screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID602229, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
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14
[SID103163101]
Identification of inhibitors of RAD54 Measured in Biochemical System Using Plate Reader - 2159-01_Inhibitor_SinglePoint_HTS_Activity [AID602329, Type: screening]DNA repair and recombination protein RAD54-like [Homo sapiens] [gi:216548193]
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15
[SID103163101]
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1). [AID720700, Type: screening]Phospholipase C, gamma 1 [Homo sapiens] [gi:223459640]
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16
[SID103163101]
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay [AID624354, Type: screening]tumor necrosis factor receptor superfamily member 10B isoform 1 precursor [Homo sapiens] [gi:224494019]
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17
[SID103163101]
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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18
[SID103163101]
Screen for inhibitors of the SWI/SNF chromatin remodeling complex (esBAF) in mouse embryonic stem cells with Luciferase reporter assay Measured in Cell-Based System Using Plate Reader - 2141-01_Inhibitor_SinglePoint_HTS_Activity [AID602393, Type: screening]transcription activator BRG1 isoform 1 [Mus musculus] [gi:291463269]
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19
[SID103163101]
Potency qHTS of PTHR Inhibitors: Primary Screen [AID743266, Type: confirmatory]parathyroid hormone/parathyroid hormone-related peptide receptor precursor [Homo sapiens] [gi:296080761]
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20
[SID103163101]
Potency qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen [AID720707, Type: confirmatory]Rap guanine nucleotide exchange factor 3 [gi:317373593]
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