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MLS003123961 (CID 49790676) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Inactive(183)
 
 
Inconclusive(7)
 
 
Unspecified(4)
 
 
Top Targets:
7TM GPCR Srsx(13)
 
 
 
7TM GPCR Srx(9)
 
 
 
RasGEF(4)
 
 
Toxin trans(3)
 
 
Anthrax-tox M(3)
 
 
BioAssay Types:
Screening(156)
 
 
 
 
Confirmatory(41)
 
 
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(34)
 
 
 
 
IC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 188    Data Row: 209   Total Pages: 11   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103075680]
Potency 16.3601qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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2
[SID103075680]
Potency 23.1093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID103075680]
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R [AID540308, Type: screening]melanocortin receptor 4 [Homo sapiens] [gi:119508433]
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4
[SID103075680]
Luminescence-based cell-based high throughput confirmation assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) [AID602192, Type: screening]melanocortin receptor 4 [Homo sapiens] [gi:119508433]
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5
[SID103075680]
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify nonselective Ga16 antagonists [AID651952, Type: screening]guanine nucleotide-binding protein subunit alpha-15 [Homo sapiens] [gi:156104883]
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6
[SID103075680]
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify nonselective agonists [AID651787, Type: screening]guanine nucleotide-binding protein subunit alpha-15 [Homo sapiens] [gi:156104883]
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7
[SID103075680]
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID602194, Type: screening]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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8
[SID103075680]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
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9
[SID103075680]
Single concentration confirmation of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651629, Type: screening]
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10
[SID103075680]
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify hTAAR1 agonists that also desensitize TAAR1 receptor response. [AID651951, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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11
[SID103075680]
Fluorescence-based cell-based primary high throughput confirmation assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) [AID651783, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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12
[SID103075680]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) [AID624466, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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13
[SID103075680]
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) [AID624467, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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14
[SID103075680]
HTS Assay for Peg3 Promoter Inhibitors [AID588405, Type: screening]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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15
[SID103075680]
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID602194, Type: screening]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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16
[SID103075680]
IC50_1_TAG_DAPI 19.041Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_5, Type: confirmatory]
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17
[SID103075680]
IC50_2_TAG_DAPI 20.405Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_6, Type: confirmatory]
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18
[SID103075680]
IC50_1_TAG 25Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_2, Type: confirmatory]
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19
[SID103075680]
IC50_2_TAG 25Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_3, Type: confirmatory]
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20
[SID103075680]
Potency 2.5119qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen [AID720542, Type: confirmatory]apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] [gi:23496270]
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