Bookmark and Share
MLS003120467 (CID 49789464) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(193)
 
 
Inconclusive(4)
 
 
Unspecified(6)
 
 
Top Targets:
HIF-1a CTAD(13)
 
 
 
 
7TM GPCR Srsx(10)
 
 
7TM GPCR Srx(7)
 
 
RasGEF(4)
 
 
Anthrax-tox M(3)
 
 
BioAssay Types:
Screening(154)
 
 
 
 
Confirmatory(44)
 
 
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(34)
 
 
 
IC50(10)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 187    Data Row: 210   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103073926]
IC50_HIF-2a_PANC_Mean 1.85Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581_7, Type: confirmatory]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
View
2
[SID103073926]
IC50_HIF-1a_Mean 51.45Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581_1, Type: confirmatory]hypoxia-inducible factor 1-alpha isoform 1 [Homo sapiens] [gi:4504385]
View
3
[SID103073926]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2) [AID651957, Type: screening]nuclear receptor coactivator 2 [Homo sapiens] [gi:5729858]
View
4
[SID103073926]
IC50_1_HIF-1a Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581_4, Type: confirmatory]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
View
5
[SID103073926]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
View
6
[SID103073926]
uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
View
7
[SID103073926]
Single concentration confirmation of uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID651580, Type: screening]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
View
8
[SID103073926]
IC50_2_HIF-2a 0.777Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581_6, Type: confirmatory]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
View
9
[SID103073926]
IC50_1_HIF-2a 0.938Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581_5, Type: confirmatory]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
View
10
[SID103073926]
IC50_2_HIF-2a_PANC 1.673Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581_9, Type: confirmatory]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
View
11
[SID103073926]
IC50_1_HIF-2a_PANC 2.03Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581_8, Type: confirmatory]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
View
12
[SID103073926]
IC50_1_HIF-1a 3.893Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581_2, Type: confirmatory]hypoxia-inducible factor 1-alpha isoform 1 [Homo sapiens] [gi:4504385]
View
13
[SID103073926]
IC50_2_HIF-1a 99Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581_3, Type: confirmatory]hypoxia-inducible factor 1-alpha isoform 1 [Homo sapiens] [gi:4504385]
View
14
[SID103073926]
IC50_1_HIF-1a 3.893Dose response confirmation of uHTS identification of HIF-2a Inhibitors in screening - selectivity counterscreen assays [AID651581, Type: confirmatory]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
View
15
[SID103073926]
VEID(2) R110 Enzymatic Primary HTS to identify Inhibitors of Caspase 6 Measured in Biochemical System Using Plate Reader - 7052-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID686996, Type: screening]Caspase 6, apoptosis-related cysteine peptidase [Homo sapiens] [gi:13325293]
View
16
[SID103073926]
uHTS identification of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID602261, Type: screening]fatty acid synthase [Homo sapiens] [gi:41872631]
View
17
[SID103073926]
uHTS identification of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay [AID588489, Type: screening]polyadenylate-binding protein 1 [Homo sapiens] [gi:46367787]
View
18
[SID103073926]
S100A4: HTS Measured in Biochemical System Using Plate Reader - 7045-01_Inhibitor_SinglePoint_HTS_Activity [AID652163, Type: screening]S100A4, partial [Homo sapiens] [gi:47496637]
View
19
[SID103073926]
uHTS identification of small molecule activators of alpha dystroglycan glycosylation [AID624168, Type: screening]LARGE [Homo sapiens] [gi:47678551]
View
20
[SID103073926]
Potency qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
View