SureCN2716077
(CID
49783214
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
2
)
Unspecified(2)
Top Targets:
HAD like(
2
)
BioAssay Types:
Literature(
4
)
BioActivity Types:
IC50(
2
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 4 Data Row: 4 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
123085377
]
Active
IC50
0.079
Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assay [AID
517036
, Type: Literature]
Bifunctional epoxide hydrolase 2 [gi:
67476665
]
View
X
Row No.
1
Structure
Substance
SID
123085377
CID
49783214
Outcome
Active
IC50
0.079 [uM]
BioAssay
Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assay
AID
517036
BioAssay type
Literature
Target
Bifunctional epoxide hydrolase 2 [gi:
67476665
]
PubMed
20812725
Data Table
2
[SID
123085377
]
Active
IC50
0.079
Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assay [AID
517036
, Type: Literature]
Bifunctional epoxide hydrolase 2 [gi:
67476665
]
View
X
Row No.
2
Structure
Substance
SID
123085377
CID
49783214
Outcome
Active
IC50
0.079 [uM]
BioAssay
Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assay
AID
517036
BioAssay type
Literature
Target
Bifunctional epoxide hydrolase 2 [gi:
67476665
]
PubMed
20812725
Data Table
3
[SID
123085377
]
Active
IC50
0.11
Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assay [AID
517038
, Type: Literature]
Bifunctional epoxide hydrolase 2 [gi:
1708375
]
View
X
Row No.
3
Structure
Substance
SID
123085377
CID
49783214
Outcome
Active
IC50
0.11 [uM]
BioAssay
Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assay
AID
517038
BioAssay type
Literature
Target
Bifunctional epoxide hydrolase 2 [gi:
1708375
]
PubMed
20812725
Data Table
4
[SID
123085377
]
Unspecified
Antiinflammatory activity in Sprague-Dawley rat assessed as reduction in carrageenan-induced inflammatory pain at 10 uL, intraplanter [AID
517037
, Type: Literature]
View
X
Row No.
4
Structure
Substance
SID
123085377
CID
49783214
Outcome
Unspecified
BioAssay
Antiinflammatory activity in Sprague-Dawley rat assessed as reduction in carrageenan-induced inflammatory pain at 10 uL, intraplanter
AID
517037
BioAssay type
Literature
Target
PubMed
20812725
Data Table
5
[SID
123085377
]
Unspecified
Lipophilicity, log P of the compound [AID
517035
, Type: Literature]
View
X
Row No.
5
Structure
Substance
SID
123085377
CID
49783214
Outcome
Unspecified
BioAssay
Lipophilicity, log P of the compound
AID
517035
BioAssay type
Literature
Target
PubMed
20812725
Data Table