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BioActivity Data for Compound MLS003124447 (CID 49778840)

BioActivity Outcomes:
Active(6)
 
 
Inactive(194)
 
 
Inconclusive(2)
 
 
Top Targets:
7tm 4(17)
 
 
RasGEF(4)
 
 
Toxin trans(3)
 
 
NR DBD CAR(3)
 
 
Bromo SNF2L2(3)
 
 
 
BioAssay Types:
Screening(153)
 
 
 
 
Confirmatory(37)
 
 
 
 
Literature(9)
 
 
BioAssay Categories:
Organism-base..(5)
 
 
 
Biochemical(51)
 
 
 
Toxicity(2)
 
 
Cell-based(58)
 
 
 
 
BioActivity Types:
Potency(35)
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 188    Data Row: 202   Total Pages: 11   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103051242]
IC50 2.179Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID652135, Type: confirmatory]fructose-bisphosphate aldolase [Mycobacterium tuberculosis H37Rv] [gi:15607504]
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2
[SID103051242]
IC50 3.458Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Fluorescence-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) dose response assay to identify assay artifacts [AID652145, Type: confirmatory]
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3
[SID103051242]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID588726, Type: screening]fructose-bisphosphate aldolase [Mycobacterium tuberculosis H37Rv] [gi:15607504]
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4
[SID103051242]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM) [AID652017, Type: screening]SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens] [gi:119579215]
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5
[SID103051242]
Luminescence-based cell-based primary high throughput confirmation assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM) [AID652260, Type: screening]SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a [Homo sapiens] [gi:119579215]
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6
[SID103051242]
Counterscreen for activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM): Luminescence-based cell-based high throughput screening assay to identify non-selective compounds using the VP16 reporter assay [AID686939, Type: screening]
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7
[SID103051242]
Potency qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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8
[SID103051242]
Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition [AID720647, Type: screening]
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9
[SID103051242]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
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10
[SID103051242]
High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_SinglePoint_HTS_Activity_Set2 [AID743238, Type: screening]
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11
[SID103051242]
Inhibition of Alexa 488-Fibronectin deposition #on AH1F cell monolayers Measured in Cell-Based System Using Plate Reader - 7059-01_Inhibitor_SinglePoint_HTS_Activity [AID743247, Type: screening]
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12
[SID103051242]
Potency High Throughput Screening for Foot and Mouth Disease Virus Antivirals [AID1159524, Type: confirmatory]
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13
[SID103051242]
Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_SinglePoint_HTS_Activity [AID743287, Type: screening]
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14
[SID103051242]
Wnt/Beta-catenin HTS Measured in Cell-Based System Using Plate Reader - 2161-01_Activator_SinglePoint_HTS_Activity [AID743398, Type: screening]
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15
[SID103051242]
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity [AID743397, Type: screening]
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16
[SID103051242]
Full deck counterscreen for positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602247, Type: screening]
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17
[SID103051242]
uHTS determination of small molecule cytotoxicity in a fluorescence assay to identify cystic fibrosis induced NFkb Inhibitors [AID602141, Type: screening]
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18
[SID103051242]
Full deck counterscreen for agonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602248, Type: screening]
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19
[SID103051242]
Whole cell Yeast HTS to identify compounds modulating the fidelity of the start codon recognition in eukaryotes. Measured in Whole Organism System Using Plate Reader - 2155-01_Other_SinglePoint_HTS_Activity [AID602363, Type: screening]
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20
[SID103051242]
Full deck counterscreen for antagonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective inhibitors and assay artifacts using the parental CHOK1 cell line [AID602250, Type: screening]
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