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Propyl Gallate (CID 4947) - Compound BioActivity Data
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BioActivity Outcomes:
Active(47)
 
 
Inactive(224)
 
 
Inconclusive(94)
 
 
Unspecified(67)
 
 
Top Targets:
NR LBD PPAR(23)
 
 
 
NR LBD AR(23)
 
 
 
NR LBD ER(23)
 
 
 
 
NR LBD GR(14)
 
 
 
 
NR LBD TR(13)
 
 
 
BioAssay Types:
Confirmatory(268)
 
 
 
 
Literature(83)
 
 
 
 
 
Summary(63)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(257)
 
 
 
 
IC50(20)
 
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 279    Data Row: 432   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103166768]
IC50 1.41Antioxidant activity assessed by superoxide anion scavenging assay [AID401336, Type: Literature]
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2
[SID103166768]
MIC 3Inhibition of iron-dependent peroxidation of rabbit vesicular membrane lipids (minimum test concentration that gave greater than 50% inhibition). [AID165766, Type: Literature]
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3
[SID144207080]
Potency-Replicate_1 4.2163qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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4
[SID103166768]
IC50 4.4Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID468431, Type: Literature]
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5
[SID103166768]
IC50 4.5Inhibition of microsomal lipid peroxidation induced by CCl4/NADPH in rat liver [AID195238, Type: Literature]
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6
[SID103166768]
IC50 4.9Inhibition of microsomal lipid peroxidation induced by [Fe(2+)]/ascorbate in rat liver [AID195240, Type: Literature]
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7
[SID144207080]
AhR Potency (uM) 5.01111qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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8
[SID103166768]
IC50 8Inhibition of microsomal lipid peroxidation induced by [Fe(3+)]-ADP/NADPH in rat liver [AID195241, Type: Literature]
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9
[SID144207080]
Potency-Replicate_1 9.5205qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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10
[SID144207080]
Potency 9.6885qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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11
[SID103166768]
IC50 12Cytotoxicity against mouse WEHI231 cells [AID732053, Type: Literature]
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12
[SID144207080]
Potency-Replicate_1 13.3332qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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13
[SID144207080]
Potency-Replicate_1 13.3332qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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14
[SID144207080]
Potency-Replicate_1 14.9601qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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15
[SID144210380]
Potency-Replicate_1 15.3553qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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16
[SID144207080]
Ratio Potency (uM) 16.9136qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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17
[SID144209484]
Ratio Potency (uM) 17.812qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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18
[SID144209484]
Potency-Replicate_1 19.2329qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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19
[SID144209484]
AhR Potency (uM) 19.2329qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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20
[SID144209484]
Potency-Replicate_1 19.4008qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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21
[SID144207080]
Ratio Potency (uM) 22.8175qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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22
[SID144207080]
Potency-Replicate_1 23.7101qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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23
[SID144209484]
Potency-Replicate_1 24.2128qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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24
[SID144210380]
Ratio Potency (uM) 24.3365qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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25
[SID103166768]
IC50 24.6Superoxide radical scavenging activity by NBT reduction assay [AID289317, Type: Literature]
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26
[SID144207080]
Potency 25.1189qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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27
[SID144207080]
Potency-Replicate_1 26.6032qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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28
[SID144209484]
Potency-Replicate_1 27.1672qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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29
[SID144209484]
Potency-Replicate_1 27.1672qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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30
[SID144210380]
Potency-Replicate_1 27.306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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31
[SID103166768]
IC50 30Antioxidant activity assessed as DPPH radical scavenging activity [AID378144, Type: Literature]
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32
[SID103166768]
IC50 30.46Antioxidant activity assessed as DPPH free radical scavenging activity in cell-free system after 30 mins [AID536653, Type: Literature]
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33
[SID144210380]
Potency-Replicate_1 30.6379qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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34
[SID103166768]
IC50 33.9IC50 value was evaluated by measuring the 50% inhibition of peroxyl scavenging activity. [AID195236, Type: Literature]
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35
[SID144209484]
Ratio Potency (uM) 38.7129qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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36
[SID103166768]
IC50 40Cytotoxicity against mouse L929 cells [AID732052, Type: Literature]
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37
[SID103166768]
IC50 46.1Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins [AID335901, Type: Literature]
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38
[SID144209484]
Potency-Replicate_1 48.3109qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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39
[SID144210380]
Potency-Replicate_1 48.5577qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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40
[SID144209484]
Potency-Replicate_1 54.2058qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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41
[SID144210380]
Ratio Potency (uM) 54.9544qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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42
[SID144209484]
Ratio Potency (uM) 56.3264qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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43
[SID144210380]
Ratio Potency (uM) 58.829qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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44
[SID144210380]
Potency-Replicate_1 61.1306qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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45
[SID144210380]
Potency-Replicate_1 61.6448qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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46
[SID144209484]
qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720725, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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47
[SID144207080]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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48
[SID103166768]
IC50 50Antioxidative activity was evaluated by using the lipid peroxidation of guinea pig liver microsomes [AID78013, Type: Literature]
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49
[SID103166768]
IC50 66.7Antioxidant activity assessed by singlet oxygen scavenging assay [AID401338, Type: Literature]
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50
[SID103166768]
EC50 84Antioxidant activity was evaluated by measuring the inhibition of oxidation of ABTS to ABTS+ by metmyoglobin in the presence of H2O2. [AID228862, Type: Literature]
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