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Prometryne (CID 4929) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(567)
 
 
Inconclusive(36)
 
 
Unspecified(15)
 
 
Top Targets:
7tm 4(23)
 
 
NR LBD PPAR(21)
 
 
 
NR LBD AR(16)
 
 
 
NR LBD ER(16)
 
 
 
NR LBD VDR(12)
 
 
 
BioAssay Types:
Confirmatory(298)
 
 
 
 
 
Screening(225)
 
 
 
Summary(48)
 
 
 
Literature(22)
 
 
 
BioActivity Types:
Potency(327)
 
 
 
 
 
IC50(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 478    Data Row: 620   Total Pages: 31   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50107261]
Potency-Replicate_1 14.1254qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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2
[SID174505168]
Herbicidal activity against hydroponic culture of s-triazine-susceptible Poa annua at 1000 ppm after 14 days [AID1109828, Type: other]
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3
[SID174505168]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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4
[SID174505168]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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5
[SID174505168]
Toxicity in Gossypium hirsutum (cotton) assessed as formation of injury to cotton [AID1088372, Type: Literature]
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6
[SID174505168]
Herbicidal activity against glyphosate-resistant Conyza canadensis (horseweed) assessed as residual control at 1120 g a.i./ha treated during autumn and spring measured 8 weeks after treatment [AID1088388, Type: Literature]
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7
[SID174505168]
Herbicidal activity against glyphosate-resistant Conyza canadensis (horseweed) assessed as residual control at 1120 g a.i./ha treated during autumn and spring measured 6 weeks after treatment [AID1088389, Type: Literature]
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8
[SID174505168]
Herbicidal activity against glyphosate-resistant Conyza canadensis (horseweed) assessed as residual control at 1120 g a.i./ha treated during autumn and spring measured 4 weeks after treatment [AID1088390, Type: Literature]
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9
[SID174505168]
Herbicidal activity against Cyperus rotundus assessed as total dry weight at 2.5 kg/ha applied as spray before seed sowing (Rvb = 4.1 MT/ha) [AID1097892, Type: Literature]
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10
[SID174505168]
Herbicidal activity against Malva sylvestris assessed as total dry weight at 2.5 kg/ha applied as spray before seed sowing (Rvb = 4.1 MT/ha) [AID1097893, Type: Literature]
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11
[SID174505168]
Herbicidal activity against Chenopodium murale assessed as total dry weight at 2.5 kg/ha applied as spray before seed sowing (Rvb = 4.1 MT/ha) [AID1097894, Type: Literature]
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12
[SID174505168]
Herbicidal activity against Cyperus rotundus assessed as total fresh weight at 2.5 kg/ha applied as spray before seed sowing (Rvb = 23.6 MT/ha) [AID1097937, Type: Literature]
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13
[SID174505168]
Herbicidal activity against Chenopodium murale assessed as total fresh weight at 2.5 kg/ha applied as spray before seed sowing (Rvb = 23.6 MT/ha) [AID1097938, Type: Literature]
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14
[SID174505168]
Herbicidal activity against Malva sylvestris assessed as total fresh weight at 2.5 kg/ha applied as spray before seed sowing (Rvb = 23.6 MT/ha) [AID1097939, Type: Literature]
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15
[SID174505168]
Phytotoxicity in Allium cepa (onion) seedling assessed as total fresh weight at 2.5 kg/ha applied as spray before seed sowing (Rvb = 7.71 MT/ha) [AID1097968, Type: Literature]
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16
[SID50107261]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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17
[SID89854492]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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18
[SID26747731]
Potency 0.631qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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19
[SID144209536]
Potency-Replicate_1 27.1672qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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20
[SID144209536]
Potency-Replicate_1 60.8199qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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