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pomiferin (CID 4871) - Compound BioActivity Data
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BioActivity Outcomes:
Active(57)
 
 
Inactive(444)
 
 
Inconclusive(72)
 
 
Unspecified(82)
 
 
Top Targets:
7TM GPCR Srx(12)
 
 
p450(11)
 
 
 
 
7TM GPCR Srsx(11)
 
 
HSD10-like SD..(6)
 
 
PLDc mTdp1 2(5)
 
 
 
BioAssay Types:
Confirmatory(270)
 
 
 
 
 
Screening(226)
 
 
 
 
Literature(28)
 
 
 
 
BioActivity Types:
Potency(172)
 
 
 
 
 
IC50(9)
 
 
 
 
AC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 574    Data Row: 655   Total Pages: 33   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124876949]
Potency 0.5805qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID124876949]
Potency 0.7308qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID92763926]
AC50_uM 0.809DiI Quencher Assay Measured in Biochemical System Using Plate Reader - 2085-08_Inhibitor_Dose_CherryPick_Activity [AID540326, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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4
[SID103536665]
IC50 1.05Inhibition of HDAC in HeLa cells [AID300832, Type: Literature]
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5
[SID92763926]
Potency 1.2995qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID103536665]
GI50 1.32Growth inhibition of human HCT15 cells after 21 hrs by MTT assay [AID300838, Type: Literature]
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7
[SID92763926]
Potency 1.4581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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8
[SID4252500]
Potency 1.9953qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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9
[SID103536665]
GI50 2.92Growth inhibition of human MDA-MB-231 cells after 21 hrs by MTT assay [AID300836, Type: Literature]
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10
[SID4252500]
Potency 3.1623qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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11
[SID103536665]
GI50 3.18Growth inhibition of human ACHN cells after 21 hrs by MTT assay [AID300834, Type: Literature]
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12
[SID103536665]
GI50 3.34Growth inhibition of human LOX-IMVI cells after 21 hrs by MTT assay [AID300837, Type: Literature]
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13
[SID26749147]
Potency 3.5481Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
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14
[SID103536665]
GI50 3.95Growth inhibition of human PC3 cells after 21 hrs by MTT assay [AID300833, Type: Literature]
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15
[SID4252500]
Potency 3.9811qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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16
[SID103536665]
GI50 5.14Growth inhibition of human NCI-H23 cells after 21 hrs by MTT assay [AID300835, Type: Literature]
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17
[SID92763926]
AC50_uM 8.751Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
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18
[SID92763926]
Potency 8.9125qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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19
[SID103536665]
IC50 9.1Antioxidant activity assessed as hypochlorous acid scavenging activity by fluorescence assay [AID767582, Type: Literature]
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20
[SID92763926]
Potency 9.2A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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