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phosalone (CID 4793) - Compound BioActivity Data
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BioActivity Outcomes:
Active(33)
 
 
Inactive(214)
 
 
Inconclusive(58)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD TR(12)
 
 
 
 
NR LBD VDR(11)
 
 
 
 
BioAssay Types:
Confirmatory(227)
 
 
 
 
Summary(48)
 
 
 
 
Screening(21)
 
 
Literature(2)
 
 
BioActivity Types:
Potency(257)
 
 
 
 
IC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 207    Data Row: 308   Total Pages: 16   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26747709]
Potency 0.7943qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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2
[SID144211128]
Potency-Replicate_1 9.6885qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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3
[SID26753686]
Potency-Replicate_1 10qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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4
[SID144211128]
Ratio Potency (uM) 10.0676qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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5
[SID144209492]
Ratio Potency (uM) 26.1041qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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6
[SID26753686]
Potency 27.306qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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7
[SID144211128]
Potency-Replicate_1 27.306qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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8
[SID144211128]
Potency-Replicate_1 27.306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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9
[SID144211128]
Potency-Replicate_1 27.306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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10
[SID144209492]
Potency-Replicate_1 29.2893qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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11
[SID144211128]
Potency-Replicate_1 30.6379qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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12
[SID144209492]
Potency-Replicate_1 32.8631qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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13
[SID144209492]
Potency-Replicate_1 32.8631qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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14
[SID144209492]
AhR Potency (uM) 32.8631qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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15
[SID144211128]
AhR Potency (uM) 33.082qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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16
[SID26747709]
Potency 35.4813Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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17
[SID144209492]
Potency-Replicate_1 46.4204qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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18
[SID144211128]
Potency-Replicate_1 54.4827qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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19
[SID144211128]
Ratio Potency (uM) 54.941qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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20
[SID26747709]
Potency 56.2341qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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