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Phenylbutazone (CID 4781) - Compound BioActivity Data
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BioActivity Outcomes:
Active(53)
 
 
Inactive(1651)
 
 
Inconclusive(242)
 
 
Unspecified(1710)
 
 
Top Targets:
7tm 4(92)
 
 
 
 
NR LBD PPAR(42)
 
 
 
NR LBD ER(39)
 
 
 
 
 
NR LBD AR(33)
 
 
 
 
p450(27)
 
 
 
 
 
BioAssay Types:
Confirmatory(1068)
 
 
 
 
 
Screening(625)
 
 
 
Literature(453)
 
 
 
 
 
Summary(89)
 
 
 
 
BioActivity Types:
Potency(876)
 
 
 
 
 
IC50(194)
 
 
 
 
 
EC50(11)
 
 
Ki(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2913    Data Row: 3656   Total Pages: 183   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103175225]
IC50 3Compound was evaluated for inhibition of Prostaglandin G/H synthase 1 [AID162309, Type: confirmatory]
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2
[SID855958]
Potency 3.2944Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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3
[SID103175225]
IC50 3.79Inhibitory activity of the compound against canine COX-2 [AID220492, Type: Literature]Prostaglandin G/H synthase-2 [gi:75047671]
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4
[SID855958]
IC50_MICROM 5.3Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands [AID519, Type: confirmatory]fMet-Leu-Phe receptor [Homo sapiens] [gi:4503779]
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5
[SID144203794]
Potency-Replicate_1 7.4978qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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6
[SID17389760]
Potency-Replicate_1 7.9433qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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7
[SID90341773]
Potency 10qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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8
[SID103175225]
IC50 10Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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9
[SID103175225]
IC50 10Inhibition of PGH synthase in tissues with lower lipid peroxide concentrations [AID155368, Type: Literature]
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10
[SID50104199]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 3D7 [AID1876, Type: confirmatory]
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11
[SID50104199]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2 [AID1883, Type: confirmatory]
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12
[SID144203794]
Ratio Potency (uM) 11.607qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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13
[SID103175225]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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14
[SID103175225]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay [AID524792, Type: Literature]
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15
[SID103175225]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay [AID524794, Type: Literature]
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16
[SID103175225]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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17
[SID103175225]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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18
[SID104171220]
Potency 13.4591Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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19
[SID50104199]
Potency 14.1254qHTS for differential inhibitors of proliferation of Plasmodium falciparum line GB4 [AID1816, Type: confirmatory]
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20
[SID103175225]
IC50 15Compound was tested for inhibition of prostaglandin synthetase when administered perorally [AID160905, Type: Literature]
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