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Phenolphthalein (CID 4764) - Compound BioActivity Data
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BioActivity Outcomes:
Active(72)
 
 
Inactive(1315)
 
 
Inconclusive(189)
 
 
Unspecified(49)
 
 
Top Targets:
NR LBD PPAR(40)
 
 
 
 
NR LBD ER(30)
 
 
 
 
7TM GPCR Srx(25)
 
 
NR LBD AR(25)
 
 
 
 
7TM GPCR Srsx(23)
 
 
BioAssay Types:
Confirmatory(710)
 
 
 
 
 
Screening(617)
 
 
 
 
Literature(127)
 
 
 
 
 
Summary(72)
 
 
 
 
BioActivity Types:
Potency(639)
 
 
 
 
 
IC50(47)
 
 
 
 
EC50(17)
 
 
 
 
Ki(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1135    Data Row: 1625   Total Pages: 82   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103260137]
Ki 1.2Inhibition of human thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assay [AID610981, Type: Literature]Thymidylate synthase [gi:136611]
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2
[SID103260137]
Ki 1.4Inhibition of Enterococcus faecalis thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assay [AID610985, Type: Literature]Thymidylate synthase [gi:62901361]
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3
[SID855935]
EC50 1 1.8Identification of Novel Modulators of Cl- dependent Transport Process via HTS; Dose-dependent Assay with KCC2 [AID1736, Type: confirmatory]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
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4
[SID144209417]
Ratio Potency (uM) 1.91937qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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5
[SID144204389]
Potency-Replicate_1 3.3747qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID144210602]
Potency-Replicate_1 3.8905qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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7
[SID855935]
Potency 3.9811qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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8
[SID144210602]
Ratio Potency (uM) 4.36519qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID144204389]
Ratio Potency (uM) 4.58742qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
10
[SID103260137]
Ki 4.7Inhibition of Lactobacillus casei thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assay [AID610987, Type: Literature]Thymidylate synthase [gi:136612]
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11
[SID103260137]
Ki 4.7In vitro inhibition of Lactobacillus casei Thymidylate synthase. [AID211817, Type: Literature]
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12
[SID17389766]
Potency 6.3096qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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13
[SID855935]
IC50 6.66718Image-Based HTS for Selective Antagonists for GPR55 [AID2013, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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14
[SID144204389]
Potency-Replicate_1 11.8832qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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15
[SID144210602]
Ratio Potency (uM) 14.3405qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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16
[SID17389766]
Potency 15.8489qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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17
[SID17389766]
Potency 15.8489qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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18
[SID17389766]
Potency 15.8489MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Dead Cells [AID960, Type: confirmatory]
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19
[SID144209417]
Potency-Replicate_1 17.1064qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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20
[SID144210602]
Potency-Replicate_1 19.4938qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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