Phenacetin (CID 4754) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(10)
 
 
Inactive(906)
 
 
Inconclusive(59)
 
 
Unspecified(1550)
 
 
Top Targets:
7TM GPCR Srx(27)
 
 
 
p450(21)
 
 
 
 
7TM GPCR Srsx(16)
 
 
 
NR LBD TR(12)
 
 
 
NR LBD ROR li..(11)
 
 
BioAssay Types:
Confirmatory(469)
 
 
 
 
 
Screening(334)
 
 
Literature(115)
 
 
 
 
 
BioActivity Types:
Potency(374)
 
 
 
 
IC50(159)
 
 
 
 
EC50(4)
 
 
Ki(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2262    Data Row: 2525   Total Pages: 51   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48414293]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
2
[SID48414293]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
View
3
[SID48414293]
 DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
View
4
[SID48414293]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
View
5
[SID48414293]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
View
6
[SID48416402]
 DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
View
7
[SID50086861]
 Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
View
8
[SID103179006]
 Phospholipidosis-positive literature compound observed in rat [AID540237, Type: Literature]
View
9
[SID11112166]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
View
10
[SID11112166]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
View
11
[SID11112166]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
View
12
[SID11112166]
 Cytochrome panel assay with activity outcomes [AID1851_4, Type: other]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
View
13
[SID11112166]
 Cytochrome panel assay with activity outcomes [AID1851_4, Type: other]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
View
14
[SID103179006]
IC50 200TP_TRANSPORTER: inhibition of Adefovir uptake in OAT1-expressing CHO cells [AID681160, Type: other]Solute carrier family 22 member 6 [gi:74762955]
View
15
[SID103179006]
Ki 488TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes [AID681340, Type: other]Solute carrier family 22 member 6 [gi:81886651]
View
16
[SID50086861]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
17
[SID50086861]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
18
[SID103179006]
IC50 DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) [AID625146, Type: other]Arachidonate 15-lipoxygenase [gi:126397]
View
19
[SID103179006]
IC50 DRUGMATRIX: Peptidase, Angiotensin Converting Enzyme enzyme inhibition (substrate: FAPGG) [AID625173, Type: other]Angiotensin-converting enzyme [gi:2822103]
View
20
[SID103179006]
 Inhibition of recombinant human AKR1C3 at 50 uM [AID257050, Type: Literature]Aldo-keto reductase family 1 member C3 [gi:308153646]
View
21
[SID103179006]
IC50 DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) [AID625198, Type: other]Alpha-1D adrenergic receptor [gi:1168244]
View
22
[SID103179006]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808) [AID625220, Type: other]5-hydroxytryptamine receptor 4 [gi:6224984]
View
23
[SID103179006]
IC50 DRUGMATRIX: Alpha-1B adrenergic receptor radioligand binding (ligand: prazosin) [AID625199, Type: other]Alpha-1B adrenergic receptor [gi:543734]
View
24
[SID103179006]
IC50 DRUGMATRIX: Alpha-1B adrenergic receptor radioligand binding (ligand: prazosin) [AID625199, Type: other]Alpha-1B adrenergic receptor [gi:543734]
View
25
[SID103179006]
IC50 DRUGMATRIX: Aldose Reductase enzyme inhibition (substrate: DL-Glyceraldehyde) [AID625208, Type: other]Aldose reductase [gi:1168407]
View
26
[SID103179006]
IC50 DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) [AID625228, Type: other]Androgen receptor [gi:113832]
View
27
[SID103179006]
IC50 DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) [AID625228, Type: other]Androgen receptor [gi:113832]
View
28
[SID103179006]
IC50 DRUGMATRIX: Nitric Oxide Synthase, Neuronal (nNOS) radioligand binding (ligand: [3H]L-Arginine) [AID625159, Type: other]Nitric oxide synthase, brain [gi:266646]
View
29
[SID103179006]
IC50 DRUGMATRIX: Insulin radioligand binding (ligand: [125I] Insulin) [AID625273, Type: other]Insulin receptor [gi:124531]
View
30
[SID103179006]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) [AID625191, Type: other]5-hydroxytryptamine receptor 1B [gi:112815]
View
31
[SID103179006]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) [AID625191, Type: other]5-hydroxytryptamine receptor 1B [gi:112815]
View
32
[SID103179006]
IC50 DRUGMATRIX: Chemokine CCR2B radioligand binding (ligand: [125I] MCP-1) [AID625237, Type: other]C-C chemokine receptor type 2 [gi:1168965]
View
33
[SID103179006]
IC50 DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF) [AID625168, Type: other]Platelet-activating factor receptor [gi:129557]
View
34
[SID124882016]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
35
[SID124882016]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
36
[SID103179006]
IC50 DRUGMATRIX: Tachykinin NK2 radioligand binding (ligand: [3H] SR-48968) [AID625227, Type: other]Substance-K receptor [gi:229462950]
View
37
[SID103179006]
IC50 DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P) [AID625226, Type: other]Substance-P receptor [gi:128359]
View
38
[SID103179006]
IC50 DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P) [AID625226, Type: other]Substance-P receptor [gi:128359]
View
39
[SID103179006]
IC50 DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2) [AID625229, Type: other]Thromboxane-A synthase [gi:254763392]
View
40
[SID103179006]
IC50 DRUGMATRIX: Phosphodiesterase PDE5 enzyme inhibition (substrate: [3H]cGMP + cGMP) [AID625167, Type: other]cGMP-specific 3',5'-cyclic phosphodiesterase [gi:317373261]
View
41
[SID103179006]
 DRUGMATRIX: Vasoactive Intestinal Peptide VIP1 radioligand binding (ligand: [125I] VIP) [AID625232, Type: other]Vasoactive intestinal polypeptide receptor 1 [gi:418253]
View
42
[SID103179006]
IC50 DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol) [AID625223, Type: other]Sigma non-opioid intracellular receptor 1 [gi:74752153]
View
43
[SID103179006]
IC50 DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol) [AID625223, Type: other]Sigma non-opioid intracellular receptor 1 [gi:74752153]
View
44
[SID103179006]
IC50 DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) [AID625145, Type: other]Cysteinyl leukotriene receptor 1 [gi:20138087]
View
45
[SID103179006]
IC50 DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) [AID625145, Type: other]Cysteinyl leukotriene receptor 1 [gi:20138087]
View
46
[SID103179006]
 DRUGMATRIX: Nitric Oxide Synthase, Inducible (iNOS) enzyme inhibition (substrate: L-Arginine) [AID625160, Type: other]Nitric oxide synthase, inducible [gi:266649]
View
47
[SID103179006]
IC50 DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625247, Type: other]Cytochrome P450 2C19 [gi:60416369]
View
48
[SID103179006]
IC50 DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625247, Type: other]Cytochrome P450 2C19 [gi:60416369]
View
49
[SID103179006]
 DRUGMATRIX: CYP450, 2A6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625246, Type: other]Cytochrome P450 2A6 [gi:308153612]
View
50
[SID103179006]
IC50 DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC) [AID625238, Type: other]C-C chemokine receptor type 4 [gi:1705894]
View