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BioActivity Data for Compound Phenacetin (CID 4754)

BioActivity Outcomes:
Active(11)
 
 
Inactive(1288)
 
 
Inconclusive(72)
 
 
Unspecified(1427)
 
 
Top Targets:
7tm 4(68)
 
 
 
NR LBD PPAR(34)
 
 
 
NR LBD ER(27)
 
 
 
NR LBD AR(26)
 
 
 
p450(26)
 
 
 
 
BioAssay Types:
Confirmatory(836)
 
 
 
 
 
Screening(396)
 
 
 
Literature(150)
 
 
 
 
 
Summary(72)
 
 
 
BioAssay Categories:
In vitro(8)
 
 
 
In vivo(8)
 
 
 
Biochemical(119)
 
 
 
Toxicity(93)
 
 
 
 
ADME(22)
 
 
 
Cell-based(143)
 
 
 
 
 
Organism-base..(14)
 
 
 
BioActivity Types:
Potency(669)
 
 
 
 
IC50(164)
 
 
 
 
EC50(4)
 
 
AC50(3)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2282    Data Row: 2798   Total Pages: 140   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179006]
Phospholipidosis-positive literature compound observed in rat [AID540237, Type: Literature]
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2
[SID170465554]
SW480 viability from Cell TiterGlo-screen [AID1117343, Type: screening]
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3
[SID48414293]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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4
[SID48414293]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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5
[SID48414293]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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6
[SID48414293]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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7
[SID48414293]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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8
[SID48416402]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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9
[SID50086861]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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10
[SID11112166]
Cytochrome panel assay with activity outcomes [AID1851_4, Type: other]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
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11
[SID11112166]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
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12
[SID103179006]
IC50 200TP_TRANSPORTER: inhibition of Adefovir uptake in OAT1-expressing CHO cells [AID681160, Type: Literature]Solute carrier family 22 member 6 [gi:74762955]
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13
[SID103179006]
Ki 488TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes [AID681340, Type: Literature]Solute carrier family 22 member 6 [gi:81886651]
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14
[SID103179006]
IC50 500Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay [AID721754, Type: Literature]Multidrug and toxin extrusion protein 1 [gi:74731723]
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15
[SID103179006]
Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells at 20 uM after 1.5 mins by fluorescence assay [AID721753, Type: Literature]Multidrug and toxin extrusion protein 1 [gi:74731723]
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16
[SID103179006]
IC50 DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) [AID625172, Type: confirmatory] [gi:75071465]
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17
[SID103179006]
IC50 DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625249, Type: confirmatory]Cytochrome P450 2D6 [gi:84028191]
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18
[SID103179006]
IC50 DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) [AID625251, Type: confirmatory]Cytochrome P450 3A4 [gi:116241312]
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19
[SID103179006]
IC50 DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) [AID625162, Type: confirmatory]Kappa-type opioid receptor [gi:116242691]
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20
[SID103179006]
DRUGMATRIX: Chemokine CXCR1 (IL-8A) [AID625240, Type: other]C-X-C chemokine receptor type 1 [gi:108936015]
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