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Pentobarbital (CID 4737) - Compound BioActivity Data
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BioActivity Outcomes:
Active(51)
 
 
Inactive(207)
 
 
Inconclusive(30)
 
 
Unspecified(218)
 
 
Top Targets:
Neur chan LBD(44)
 
 
 
Neur chan mem..(11)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD TR(5)
 
 
BioAssay Types:
Literature(184)
 
 
 
 
Confirmatory(128)
 
 
 
Summary(15)
 
 
Screening(5)
 
 
BioActivity Types:
Potency(138)
 
 
 
IC50(6)
 
 
 
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 392    Data Row: 506   Total Pages: 26   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103165831]
IC50 1.7Ability to allosterically modulate the binding of [35S]TBPS to gamma-aminobutyric-acid A receptor in rat brain cortical P2 membranes. [AID71697, Type: Literature]
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2
[SID103165831]
IC50 40Inhibition of [35S]TBPS binding to GABA-A receptor in rat cerebral cortex. [AID71848, Type: Literature]
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3
[SID48416394]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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4
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-3 [gi:120773]
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5
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-3 [gi:120773]
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6
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-3 [gi:120773]
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7
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-5 [gi:399519]
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8
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-5 [gi:399519]
View
9
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-5 [gi:399519]
View
10
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-3 [gi:462149]
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11
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-3 [gi:462149]
View
12
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-3 [gi:462149]
View
13
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit pi [gi:6016089]
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14
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit pi [gi:6016089]
View
15
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit pi [gi:6016089]
View
16
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit epsilon [gi:13124728]
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17
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit epsilon [gi:13124728]
View
18
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit epsilon [gi:13124728]
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19
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit theta [gi:13959382]
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20
[SID103165831]
GABA-A receptor; anion channel positive allosteric modulator [AID742652, Type: Literature]Gamma-aminobutyric acid receptor subunit theta [gi:13959382]
View